Related Diseases
Schizophrenia
Product Name
Davunetide acetate
Size
10.0mg; 25.0mg; 50.0mg
Description
Davunetide acetate is an eight amino acid peptide (NAPVSIPQ) that has been shown to provide potent neuroprotection, in vitro and in vivo. Davunetide has been shown to increase memory scores in patients suffering from amnestic mild cognitive impairment, a precursor to Alzheimer's disease and to enhance functional daily behaviors in schizophrenia patients.
Chemical Formula
C38H64N10O14
Elemental Analysis
C, 51.57; H, 7.29; N, 15.83; O, 25.31
Synonym
Davunetide acetate; AL 108; AL 208; AL-108; AL-208; H2N-L-Asn-L-Ala-L-Pro-L-Val-L-Ser-L-Ile-L-Pro-L-Gln-COOH; NAP (peptide); NAPVSIPQ.
IUPAC/Chemical Name
L-asparaginyl-L-alanyl-L-prolyl-L-valyl-L-seryl-L-isoleucyl-L-prolyl-L-glutamine compound with acetic acid
InChi Key
FKFJZZGKZSKPFE-XVHDDEJMSA-N
InChi Code
InChI=1S/C36H60N10O12.C2H4O2/c1-6-18(4)28(35(56)46-14-8-9-23(46)31(52)41-21(36(57)58)11-12-25(38)48)44-30(51)22(16-47)42-33(54)27(17(2)3)43-32(53)24-10-7-13-45(24)34(55)19(5)40-29(50)20(37)15-26(39)49;1-2(3)4/h17-24,27-28,47H,6-16,37H2,1-5H3,(H2,38,48)(H2,39,49)(H,40,50)(H,41,52)(H,42,54)(H,43,53)(H,44,51)(H,57,58);1H3,(H,3,4)/t18-,19-,20-,21-,22-,23-,24-,27-,28-;/m0./s1
SMILES Code
O=C(N[C@H](C(N[C@H](C(N[C@H](C(N1[C@H](C(N[C@@H](CCC(N)=O)C(O)=O)=O)CCC1)=O)[C@H](CC)C)=O)CO)=O)C(C)C)[C@H]2N(C([C@@H](NC([C@H](CC(N)=O)N)=O)C)=O)CCC2.CC(O)=O
Purity
>98% (or refer to the Certificate of Analysis)
Shipping Condition
Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
Storage Condition
Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).
Solubility
To be determined
Shelf Life
>2 years if stored properly
Drug Formulation
To be determined
Stock Solution Storage
0 - 4℃ for short term (days to weeks), or -20℃ for long term (months).
HS Tariff Code
2934.99.9001