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CP-316311

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Specification

Cat. No.

SMD743

Related Diseases

Depression

Product Name

CP-316311

Size

Customizable

Price

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Description

CP-316311 is a potent and selective CRF 1 receptor antagonist with an IC50 value of 6.8 nM in receptor binding and demonstrates oral efficacy in central nervous system (CNS) in vivo models. CP-316311 was advanced to phase II depression trials to test the hypothesis that CRF 1 antagonists could be used clinically as antidepressant drugs.

CAS Number

175139-41-0

Chemical Formula

C21H29NO2

Exact Mass

327.2198

Molecular Weight

327.468

Elemental Analysis

C, 77.02; H, 8.93; N, 4.28; O, 9.77

Synonym

CP-316311; CP 316311; CP316311; CP-316,311; CP 316,311; CP316,311.

IUPAC/Chemical Name

3,6-dimethyl-4-pentan-3-yloxy-2-(2,4,6-trimethylphenoxy)pyridine

InChi Key

ZSEJGVQTBLJRCQ-UHFFFAOYSA-N

InChi Code

InChI=1S/C21H29NO2/c1-8-18(9-2)23-19-12-16(6)22-21(17(19)7)24-20-14(4)10-13(3)11-15(20)5/h10-12,18H,8-9H2,1-7H3

SMILES Code

CC1=C(OC2=NC(C)=CC(OC(CC)CC)=C2C)C(C)=CC(C)=C1

Appearance

Solid powder

Purity

>98% (or refer to the Certificate of Analysis)

Shipping Condition

Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.

Storage Condition

Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).

Solubility

Soluble in DMSO, not in water

Shelf Life

>2 years if stored properly

Drug Formulation

This drug may be formulated in DMSO

Stock Solution Storage

0 - 4℃ for short term (days to weeks), or -20℃ for long term (months).

HS Tariff Code

2934.99.9001

All of our services and products are intended for preclinical research use only and cannot be used to diagnose, treat or manage patients.