Related Diseases
Depression
Description
CP-122721 is a NK1 receptor antagonist that possesses unique antidepressant, anxiolytic, and antiemetic properties. It is also a potent and selective substance P receptor antagonist.
Chemical Formula
C20H23F3N2O2
Elemental Analysis
C, 63.15; H, 6.09; F, 14.98; N, 7.36; O, 8.41
Synonym
CP-122721; CP122721; CP 122721; UNII-R7OYP6N58F.
IUPAC/Chemical Name
(2S,3S)-N-(2-methoxy-5-(trifluoromethoxy)benzyl)-2-phenylpiperidin-3-amine
InChi Key
ZIWFCOIGUNPHPM-HKUYNNGSSA-N
InChi Code
InChI=1S/C20H23F3N2O2/c1-26-18-10-9-16(27-20(21,22)23)12-15(18)13-25-17-8-5-11-24-19(17)14-6-3-2-4-7-14/h2-4,6-7,9-10,12,17,19,24-25H,5,8,11,13H2,1H3/t17-,19-/m0/s1
SMILES Code
COc1ccc(OC(F)(F)F)cc1CN[C@H]2CCCN[C@H]2c3ccccc3
Purity
>98% (or refer to the Certificate of Analysis)
Shipping Condition
Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
Storage Condition
Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).
Solubility
Soluble in DMSO, not in water
Shelf Life
>2 years if stored properly
Drug Formulation
This drug may be formulated in DMSO
Stock Solution Storage
0 - 4℃ for short term (days to weeks), or -20℃ for long term (months).
HS Tariff Code
2934.99.9001