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Clorgyline HCl

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Specification

Cat. No.

SMD754

Related Diseases

Depression

Product Name

Clorgyline HCl

Size

100.0mg; 200.0mg; 500.0mg; 1.0g; 2.0g

Price

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Availability

2 Weeks

Description

Clorgyline, also known as Clorgiline, M&B 9302 or MB9302, is a monoamine oxidase inhibitor (MAOI) structurally related to pargyline which is described as an antidepressant. Specifically, it is an irreversible and selective inhibitor of monoamine oxidase A (MAO-A). Clorgiline was never marketed, but it has found use in scientific research. In addition to its actions as an MAOI, clorgiline has been found to bind with high affinity to the σ1 receptor (Ki = 3.2 nM) and with very high affinity to the I2 imidazoline receptor (an allosteric site on the monoamine oxidase enzyme) (Ki = 40 pM).

CAS Number

17780-75-5 (HCl)

Chemical Formula

C13H16Cl3NO

Molecular Weight

308.627

Elemental Analysis

C, 50.59; H, 5.23; Cl, 34.46; N, 4.54; O, 5.18

Synonym

Clorgyline HCl; Clorgyline hydrochloride; M&B 9302; MB 9302; MB-9302; MB9302; Clorgiline

IUPAC/Chemical Name

N-(3-(2,4-dichlorophenoxy)propyl)-N-methylprop-2-yn-1-amine hydrochloride

InChi Key

BBAZDLONIUABKI-UHFFFAOYSA-N

InChi Code

InChI=1S/C13H15Cl2NO.ClH/c1-3-7-16(2)8-4-9-17-13-6-5-11(14)10-12(13)15;/h1,5-6,10H,4,7-9H2,2H3;1H

SMILES Code

C#CCN(CCCOC1=CC=C(Cl)C=C1Cl)C.[H]Cl

Appearance

Solid powder

Purity

>98% (or refer to the Certificate of Analysis)

Shipping Condition

Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.

Storage Condition

Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).

Solubility

Soluble in DMSO

Shelf Life

>2 years if stored properly

Drug Formulation

This drug may be formulated in DMSO

Stock Solution Storage

0 - 4℃ for short term (days to weeks), or -20℃ for long term (months).

HS Tariff Code

2934.99.9001

All of our services and products are intended for preclinical research use only and cannot be used to diagnose, treat or manage patients.