Related Diseases
Depression
Product Name
Clomipramine HCl
Description
Clomipramine HCl inhibitor of mAChRs, 5-HT2/3/6/7 receptors, α1/2-adrenergic receptors, SERT, NET, and hERG K and L-type Ca channels used to treat depression, anxiety, narcolepClomipramine HCl sy, and obessive-compulisve disorder. It also acts as a FIASMA, decreases thermal and mechanical pain, and may prolong the cardiac QT interval.
CAS Number
17321-77-6 (HCl)
Chemical Formula
C19H24Cl2N2
Elemental Analysis
C, 64.96; H, 6.89; Cl, 20.18; N, 7.97
Synonym
Anafranil; Clomicalm; G-34586; G34586; G 34586; Hydiphen
IUPAC/Chemical Name
3-(3-chloro-10,11-dihydro-5H-dibenzo[b,f]azepin-5-yl)-N,N-dimethylpropan-1-amine hydrochloride
InChi Key
WIMWMKZEIBHDTH-UHFFFAOYSA-N
InChi Code
InChI=1S/C19H23ClN2.ClH/c1-21(2)12-5-13-22-18-7-4-3-6-15(18)8-9-16-10-11-17(20)14-19(16)22;/h3-4,6-7,10-11,14H,5,8-9,12-13H2,1-2H3;1H
SMILES Code
CN(C)CCCN1C2=CC(Cl)=CC=C2CCC3=CC=CC=C31.[H]Cl
Appearance
White to off-white crystalline powder.
Purity
>98% (or refer to the Certificate of Analysis)
Shipping Condition
Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
Storage Condition
Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).
Solubility
Soluble in DMSO
Shelf Life
>2 years if stored properly
Drug Formulation
This drug may be formulated in DMSO
Stock Solution Storage
0 - 4℃ for short term (days to weeks), or -20℃ for long term (months).
HS Tariff Code
2934.99.9001