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Clobenpropit HBr

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Specification

Cat. No.

SMD740

Related Diseases

Depression

Product Name

Clobenpropit HBr

Size

10.0mg; 50.0mg; 100.0mg

Price

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Availability

2 Weeks

Description

Clobenpropit, also known as VUF 9153, is a highly potent H3 antagonist and H4 partial agonist. Clobenpropit has been shown to protect NMDA-induced neuronal necrosis in cortical neuronal cell culture from rats. Clobenpropit promises neuroprotection against LPS-induced cognitive deficits by meliorating neuroinflammation and restoring the MRCC enzymes in mice. Clobenpropit protects propofol-induced apoptosis of hippocampal neurons through PI3K/AKT pathway.

CAS Number

145231-35-2 (2HBr)

Chemical Formula

C14H19Br2ClN4S

Exact Mass

467.9386

Molecular Weight

470.652

Elemental Analysis

C, 35.73; H, 4.07; Br, 33.95; Cl, 7.53; N, 11.90; S, 6.81

Synonym

Clobenpropit HBr; Clobenpropit dihydrobromide; VUF 9153; VUF-9153; VUF9153;

IUPAC/Chemical Name

3-(1H-imidazol-4-yl)propyl (4-chlorobenzyl)carbamimidothioate dihydrobromide

InChi Key

JIJQPEZAVLJZBO-UHFFFAOYSA-N

InChi Code

InChI=1S/C14H17ClN4S.2BrH/c15-12-5-3-11(4-6-12)8-18-14(16)20-7-1-2-13-9-17-10-19-13;;/h3-6,9-10H,1-2,7-8H2,(H2,16,18)(H,17,19);2*1H

SMILES Code

ClC1=CC=C(CNC(SCCCC2=CNC=N2)=N)C=C1.[H]Br.[H]Br

Appearance

Solid powder

Purity

>98% (or refer to the Certificate of Analysis)

Shipping Condition

Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.

Storage Condition

Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).

Solubility

Soluble in DMSO

Shelf Life

>3 years if stored properly

Drug Formulation

This drug may be formulated in DMSO

Stock Solution Storage

0 - 4℃ for short term (days to weeks), or -20℃ for long term (months).

HS Tariff Code

2934.99.9001

All of our services and products are intended for preclinical research use only and cannot be used to diagnose, treat or manage patients.