Inquiry

* Name

Phone

* Email

* Services or Products of Interest

Project Description

* Please note that all of our services and products are intended for preclinical research use only and cannot be used to diagnose, treat or manage patients.

* Tick to confirm the Research Use Only (RUO) statement.

Ciproxifan maleate

Inquiry

Specification

Cat. No.

SMD459

Related Diseases

Autism

Related Diseases

Schizophrenia

Product Name

Ciproxifan maleate

Size

100.0mg; 200.0mg; 500.0mg; 1.0g; 2.0g; 5.0g

Price

Inquiry

Availability

2 Weeks

Description

Ciproxifan, also known as FUB-359, is an extremely potent histamine H3 inverse agonist/antagonist. Ciproxifan produces wakefulness and attentiveness in animal studies, and produced cognitive enhancing effects without prominent stimulant effects at relatively low levels of receptor occupancy, and pronounced wakefulness at higher doses. It has therefore been proposed as a potential treatment for sleep disorders such as narcolepsy and to improve vigilance in old age, particularly in the treatment of conditions such as Alzheimer's disease. It also potentiated the effects of antipsychotic drugs, and has been suggested as an adjuvant treatment for schizophrenia.

CAS Number

184025-19-2 (maleate)

Chemical Formula

C20H22N2O6

Exact Mass

270.1368

Molecular Weight

386.404

Elemental Analysis

C, 62.17; H, 5.74; N, 7.25; O, 24.84

Synonym

FUB-359; FUB 359; FUB359; Ciproxifan. Ciproxifan maleate

IUPAC/Chemical Name

Cyclopropyl-(4-(3-1H-imidazol-4-yl)propyloxyphenyl)ketone maleate

InChi Key

RLQFKEYRALXXEJ-BTJKTKAUSA-N

InChi Code

InChI=1S/C16H18N2O2.C4H4O4/c19-16(12-3-4-12)13-5-7-15(8-6-13)20-9-1-2-14-10-17-11-18-14;5-3(6)1-2-4(7)8/h5-8,10-12H,1-4,9H2,(H,17,18);1-2H,(H,5,6)(H,7,8)/b;2-1-

SMILES Code

O=C(C1CC1)C2=CC=C(OCCCC3=CNC=N3)C=C2.O=C(O)/C=C\C(O)=O

Appearance

Solid powder

Purity

>98% (or refer to the Certificate of Analysis)

Shipping Condition

Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.

Storage Condition

Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).

Solubility

Soluble in DMSO, not in water

Shelf Life

>2 years if stored properly

Drug Formulation

This drug may be formulated in DMSO

Stock Solution Storage

0 - 4℃ for short term (days to weeks), or -20℃ for long term (months).

HS Tariff Code

2934.99.9001

All of our services and products are intended for preclinical research use only and cannot be used to diagnose, treat or manage patients.