Related Diseases
Depression
Product Name
Chlorpheniramine Maleate
Description
Chlorpheniramine maleate is a histamine H1 antagonist used in allergic reactions, hay fever, rhinitis, urticaria, and asthma. One of the most widely used of the classical antihistaminics, it generally causes less drowsiness and sedation than Promethazine. Although not generally approved as an antidepressant or anti-anxiety medication, chlorphenamine appears to have these properties as well. In addition to being an histamine H1 receptor antagonist, chlorphenamine has been shown to work as a serotonin-norepinephrine reuptake inhibitor or SNRI.
Chemical Formula
C20H23ClN2O4
Elemental Analysis
C, 61.46; H, 5.93; Cl, 9.07; N, 7.17; O, 16.37
Synonym
Chlorpheniramine Maleate; Piriton; Chlortrimeton; Deconamine; Neorestamin; Bayer Brand of Chlorpheniramine Maleate; Chlo-Amine; Chlor-100; Chlor-Trimeton;
IUPAC/Chemical Name
3-(4-chlorophenyl)-N,N-dimethyl-3-(pyridin-2-yl)propan-1-amine maleate
InChi Key
DBAKFASWICGISY-BTJKTKAUSA-N
InChi Code
InChI=1S/C16H19ClN2.C4H4O4/c1-19(2)12-10-15(16-5-3-4-11-18-16)13-6-8-14(17)9-7-13;5-3(6)1-2-4(7)8/h3-9,11,15H,10,12H2,1-2H3;1-2H,(H,5,6)(H,7,8)/b;2-1-
SMILES Code
CN(CCC(C1=CC=CC=N1)C2=CC=C(Cl)C=C2)C.O=C(O)/C=C\C(O)=O
Appearance
White crystalline solid.
Purity
>98% (or refer to the Certificate of Analysis)
Shipping Condition
Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
Storage Condition
Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).
Solubility
Soluble in DMSO, not in water
Shelf Life
>2 years if stored properly
Drug Formulation
This drug may be formulated in DMSO
Stock Solution Storage
0 - 4℃ for short term (days to weeks), or -20℃ for long term (months).
HS Tariff Code
2934.99.9001