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Chelidonic Acid

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Specification

Cat. No.

SMD702

Related Diseases

Depression

Product Name

Chelidonic Acid

Size

1.0g; 5.0g

Price

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Availability

2 Weeks

Description

Chelidonic acid is a pyran that has been found in C. majus and has diverse biological activities. It inhibits rat brain glutamate decarboxylase. Chelidonic acid reduces serum IL-6 and TNF-α levels, colonic COX-2 and prostaglandin E2 levels, and the disease activity index score in a mouse model of ulcerative colitis induced by dextran sulfate sodium. It inhibits ovalbumin challenge-induced decreases in spleen IFN-γ levels and increases in serum, spleen, and nasal mucosa IgE levels, spleen IL-4 levels, and nasal mucosa eosinophil and mast cell infiltration in a mouse model of ovalbumin-sensitized allergic rhinitis when administered at a dose of 2 mg/kg.

CAS Number

99-32-1

Chemical Formula

C7H4O6

Exact Mass

184.0008

Molecular Weight

184.103

Elemental Analysis

C, 45.67; H, 2.19; O, 52.14

Synonym

Chelidonic Acid; NSC 3979; NSC3979; NSC-3979;

IUPAC/Chemical Name

4-oxo-4H-pyran-2,6-dicarboxylic acid

InChi Key

PBAYDYUZOSNJGU-UHFFFAOYSA-N

InChi Code

InChI=1S/C7H4O6/c8-3-1-4(6(9)10)13-5(2-3)7(11)12/h1-2H,(H,9,10)(H,11,12)

SMILES Code

O=C1C=C(OC(C(O)=O)=C1)C(O)=O

Appearance

To be determined

Purity

>95% (or refer to the Certificate of Analysis)

Shipping Condition

Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.

Storage Condition

Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).

Solubility

Soluble in DMSO

Shelf Life

>3 years if stored properly

Drug Formulation

This drug may be formulated in DMSO

Stock Solution Storage

0 - 4℃ for short term (days to weeks), or -20℃ for long term (months).

HS Tariff Code

2934.99.9001

All of our services and products are intended for preclinical research use only and cannot be used to diagnose, treat or manage patients.