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Caroverine

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Specification

Cat. No.

SMD1443

Related Diseases

Schizophrenia

Product Name

Caroverine

Size

10.0mg; 50.0mg

Price

Inquiry

Availability

2 Weeks

Description

Caroverine is a nonselective NMDA and AMPA glutamate receptor antagonist, also acting as a class B calcium-channel-blocker. Pharmacologically, it has been described as a nonspecific calcium channel blocker and as an antagonist of both non-NMDA and NMDA glutamate receptors. Caroverine (Spasmium, Tinnitin, Tinnex) is a muscle-relaxing drug used in Austria and Switzerland to relieve spasms in smooth muscles (which include intestines, arteries, and other organs), and the use in those countries was extended to aid with cerebrovascular diseases there, and eventually to treat tinnitus. caroverine is also a potential chemotherapeutical agent in HNSCC cell lines.

CAS Number

23465-76-1 (free base)

Chemical Formula

C22H27N3O2

Exact Mass

365.2103

Molecular Weight

365.477

Elemental Analysis

C, 72.30; H, 7.45; N, 11.50; O, 8.76

Synonym

Caroverine; P 201-1; P-201-1; P201-1; P 2011; P-2011; P2011;

IUPAC/Chemical Name

1-(2-(Diethylamino)ethyl)-3-(p-methoxybenzyl)-2(1H)-quinoxalinone

InChi Key

MSPRUJDUTKRMLM-UHFFFAOYSA-N

InChi Code

InChI=1S/C22H27N3O2/c1-4-24(5-2)14-15-25-21-9-7-6-8-19(21)23-20(22(25)26)16-17-10-12-18(27-3)13-11-17/h6-13H,4-5,14-16H2,1-3H3

SMILES Code

O=C1N(CCN(CC)CC)C2=C(C=CC=C2)N=C1CC3=CC=C(OC)C=C3

Appearance

Solid powder

Purity

>98% (or refer to the Certificate of Analysis)

Shipping Condition

Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.

Storage Condition

Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).

Solubility

Soluble in DMSO

Shelf Life

>3 years if stored properly

Drug Formulation

This drug may be formulated in DMSO

Stock Solution Storage

0 - 4℃ for short term (days to weeks), or -20℃ for long term (months).

HS Tariff Code

2934.99.9001

All of our services and products are intended for preclinical research use only and cannot be used to diagnose, treat or manage patients.