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Carisbamate

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Specification

Cat. No.

SMD699

Related Diseases

Depression

Product Name

Carisbamate

Size

1.0mg

Price

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Availability

2 Weeks

Description

Carisbamate, also known as JNJ-10234094, RWJ 333369 and YKP-509, is an antiepileptic candidate. Carisbamate has powerful disease-modifying effects in the lithium-pilocarpine model of temporal lobe epilepsy. Carisbamate inhibits glutamate transmission in the granule cell of the dentate gyrus. Carisbamate acutely suppresses spasms in a rat model of symptomatic infantile spasms.

CAS Number

194085-75-1 (S-isomer)

Chemical Formula

C9H10ClNO3

Exact Mass

215.0349

Molecular Weight

215.633

Elemental Analysis

C, 50.13; H, 4.67; Cl, 16.44; N, 6.50; O, 22.26

Synonym

JNJ-10234094; JNJ10234094; JNJ10234094; RWJ 333369; RWJ333369; RWJ-333369; YKP-509; YKP-509; YKP-509; Carisbamate. trade name Comfyde.

IUPAC/Chemical Name

(S)-2-(2-chlorophenyl)-2-hydroxyethyl carbamate

InChi Key

OLBWFRRUHYQABZ-MRVPVSSYSA-N

InChi Code

InChI=1S/C9H10ClNO3/c10-7-4-2-1-3-6(7)8(12)5-14-9(11)13/h1-4,8,12H,5H2,(H2,11,13)/t8-/m1/s1

SMILES Code

O[C@@H](C1=CC=CC=C1Cl)COC(N)=O

Appearance

Solid powder

Purity

>98% (or refer to the Certificate of Analysis)

Shipping Condition

Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.

Storage Condition

Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).

Solubility

Soluble in DMSO, not in water

Shelf Life

>2 years if stored properly

Drug Formulation

This drug may be formulated in DMSO

Stock Solution Storage

0 - 4℃ for short term (days to weeks), or -20℃ for long term (months).

HS Tariff Code

2934.99.9001

All of our services and products are intended for preclinical research use only and cannot be used to diagnose, treat or manage patients.