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Cariprazine HCl

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Specification

Cat. No.

SMD542

Related Diseases

Bipolar Disorder

Related Diseases

Schizophrenia

Product Name

Cariprazine HCl

Size

100.0mg; 200.0mg; 500.0mg; 1.0g; 2.0g

Price

Inquiry

Availability

2 Weeks

Description

Cariprazine, also known as RGH-188 and MP-214, is an antipsychotic drug received FDA approval on September 17, 2015. Cariprazine acts as a D2 and D3 receptor partial agonist, with high selectivity towards the D3 receptor. Action on the dopaminergic systems makes it also potentially useful as an add-on therapy in major depressive disorder. Cariprazine is approved for schizophrenia and bipolar disorder. It has also been investigated as a potential adjunct in treatment-resistant major depressive disorder.

CAS Number

1083076-69-0 (HCl)

Chemical Formula

C21H33Cl3N4O

Exact Mass

426.1953

Molecular Weight

463.872

Elemental Analysis

C, 54.38; H, 7.17; Cl, 22.93; N, 12.08; O, 3.45

Synonym

RGH-188; RGH188; RGH 188; MP-214; MP 214; MP214; Cariprazine. trade name Vraylar; Cariprazine HCl

IUPAC/Chemical Name

3-((1r,4r)-4-(2-(4-(2,3-dichlorophenyl)piperazin-1-yl)ethyl)cyclohexyl)-1,1-dimethylurea hydrochloride

InChi Key

GPPJWWMREQHLQT-BHQIMSFRSA-N

InChi Code

InChI=1S/C21H32Cl2N4O.ClH/c1-25(2)21(28)24-17-8-6-16(7-9-17)10-11-26-12-14-27(15-13-26)19-5-3-4-18(22)20(19)23;/h3-5,16-17H,6-15H2,1-2H3,(H,24,28);1H/t16-,17-;

SMILES Code

O=C(N[C@H]1CC[C@H](CCN2CCN(C3=CC=CC(Cl)=C3Cl)CC2)CC1)N(C)C.[H]Cl

Appearance

Solid powder

Purity

>98% (or refer to the Certificate of Analysis)

Shipping Condition

Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.

Storage Condition

Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).

Solubility

Soluble in DMSO, not in water

Shelf Life

>2 years if stored properly

Drug Formulation

This drug may be formulated in DMSO

Stock Solution Storage

0 - 4℃ for short term (days to weeks), or -20℃ for long term (months).

HS Tariff Code

2934.99.9001

All of our services and products are intended for preclinical research use only and cannot be used to diagnose, treat or manage patients.