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BW 373U86

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Specification

Cat. No.

SMD724

Related Diseases

Depression

Product Name

BW 373U86

Size

Customizable

Price

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Description

BW 373U86 is an opioid analgesic drug used in scientific research.[1][2] BW373U86 is a selective agonist for the δ-opioid receptor, with approximately 15x stronger affinity for the δ-opioid than the μ-opioid receptor. It has potent analgesic and antidepressant effects in animal studies. In studies on rats, BW373U86 appears to protect heart muscle cells from apoptosis in conditions of ischemia (oxygen deprivation, such as in heart attack). The mechanism for this is complex and may be separate from its delta agonist effects.

CAS Number

150428-54-9

Chemical Formula

C27H37N3O2

Exact Mass

435.2886

Molecular Weight

435.61

Elemental Analysis

C, 74.45; H, 8.56; N, 9.65; O, 7.35

Synonym

BW 373U86; BW-373U86; BW373U86

IUPAC/Chemical Name

4-((R)-((2S,5R)-4-allyl-2,5-dimethylpiperazin-1-yl)(3-hydroxyphenyl)methyl)-N,N-diethylbenzamide

InChi Key

LBLDMHBSVIVJPM-YZIHRLCOSA-N

InChi Code

InChI=1S/C27H37N3O2/c1-6-16-29-18-21(5)30(19-20(29)4)26(24-10-9-11-25(31)17-24)22-12-14-23(15-13-22)27(32)28(7-2)8-3/h6,9-15,17,20-21,26,31H,1,7-8,16,18-19H2,2-5H3/t20-,21+,26-/m1/s1

SMILES Code

CCN(C(c1ccc([C@H](c2cc(O)ccc2)N3C[C@H](N(C[C@@H]3C)CC=C)C)cc1)=O)CC

Appearance

Solid powder

Purity

>98% (or refer to the Certificate of Analysis)

Shipping Condition

Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.

Storage Condition

Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).

Solubility

Soluble in DMSO

Shelf Life

>3 years if stored properly

Drug Formulation

This drug may be formulated in DMSO

Stock Solution Storage

0 - 4℃ for short term (days to weeks), or -20℃ for long term (months).

HS Tariff Code

2934.99.9001

All of our services and products are intended for preclinical research use only and cannot be used to diagnose, treat or manage patients.