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Brofaromine Hydrochloride

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Specification

Cat. No.

SMD108

Related Diseases

Anxiety

Related Diseases

Depression

Product Name

Brofaromine Hydrochloride

Size

Customizable

Price

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Description

Brofaromine Hydrochloride is a reversible inhibitor of monoamine oxidase A and acts on epinephrine , norepinephrine, serotonin, and dopamine. The compound was primarily researched in the treatment of depression and anxiety. Brofaromine also acts as a serotonin reuptake inhibitor, and its dual pharmacologic effects offered promise in the treatment of a wide spectrum of depressed patients while producing less severe anticholinergic side effects in comparison with older standard drugs like the tricyclic antidepressants. Unlike standard MAOIs, possible side effects do not include cardiovascular complications (hypertension) with encephalopathy, liver toxicity or hyperthermia.

CAS Number

63638-90-4 (HCl)

Chemical Formula

C14H17BrClNO2

Exact Mass

345.01312

Molecular Weight

346.65

Elemental Analysis

C, 48.51; H, 4.94; Br, 23.05; Cl, 10.23; N, 4.04; O, 9.23

Synonym

Brofaromine Hydrochloride; Brofaromine HCl; CGP-11305A; CGP-11305A.

IUPAC/Chemical Name

4-(7-Bromo-5-methoxy-2-benzofuranyl)piperidine hydrochloride

InChi Key

PUYKEOGYPYITCW-UHFFFAOYSA-N

InChi Code

InChI=1S/C14H16BrNO2.ClH/c1-17-11-6-10-7-13(9-2-4-16-5-3-9)18-14(10)12(15)8-11;/h6-9,16H,2-5H2,1H3;1H

SMILES Code

c12c(c(cc(c2)OC)Br)oc(c1)C1CCNCC1.Cl

Appearance

Solid powder

Purity

>98% (or refer to the Certificate of Analysis)

Shipping Condition

Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.

Storage Condition

Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).

Solubility

Soluble in DMSO, not in water

Shelf Life

>2 years if stored properly

Drug Formulation

This drug may be formulated in DMSO

Stock Solution Storage

0 - 4℃ for short term (days to weeks), or -20℃ for long term (months).

HS Tariff Code

2934.99.9001

All of our services and products are intended for preclinical research use only and cannot be used to diagnose, treat or manage patients.