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BRL-44408 maleate

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Specification

Cat. No.

SMD723

Related Diseases

Depression

Product Name

BRL-44408 maleate

Size

10.0mg; 25.0mg; 50.0mg

Price

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Availability

2 Weeks

Description

BRL 44408 Maleate Salt is a selective α2A-adrenoceptor antagonist (Ki = 1.7 nM and 144.5 nM at α2A and α2B-adrenergic receptors respectively). BRL 44408 Maleate Salt increases hippocampal noradrenalin release following systemic administration. BRL 44408 has potential therapeutic application in the treatment of extrapyramidal side effects produced by some antipsychotic medications.

CAS Number

681806-46-2 (maleate)

Chemical Formula

C17H21N3O4

Molecular Weight

331.37

Elemental Analysis

C, 61.62; H, 6.39; N, 12.68; O, 19.31

Synonym

BRL 44408; BRL44408; BRL-44408.

IUPAC/Chemical Name

2-[2H-(1-Methyl-1,3-dihydroisoindole)methyl]-4,5-dihydroimidazole maleate salt

InChi Key

DDIQGSUEJOOQQQ-BTJKTKAUSA-N

InChi Code

InChI=1S/C13H17N3.C4H4O4/c1-10-12-5-3-2-4-11(12)8-16(10)9-13-14-6-7-15-13;5-3(6)1-2-4(7)8/h2-5,10H,6-9H2,1H3,(H,14,15);1-2H,(H,5,6)(H,7,8)/b;2-1-

SMILES Code

CC1N(CC2=NCCN2)CC3=C1C=CC=C3.O=C(O)/C=C\C(O)=O

Appearance

Solid powder

Purity

>98% (or refer to the Certificate of Analysis)

Shipping Condition

Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.

Storage Condition

Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).

Solubility

Soluble in DMSO

Shelf Life

>2 years if stored properly

Drug Formulation

This drug may be formulated in DMSO

Stock Solution Storage

0 - 4℃ for short term (days to weeks), or -20℃ for long term (months).

HS Tariff Code

2934.99.9001

All of our services and products are intended for preclinical research use only and cannot be used to diagnose, treat or manage patients.