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BNC-210 TFA

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Specification

Cat. No.

SMD132

Related Diseases

Anxiety

Product Name

BNC-210 TFA

Size

Customizable

Price

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Description

BNC210, also known as IW-2143, is an anxiolytic drug that acts via negative allosteric modulation of the α7-nicotinic acetylcholine receptor. It is currently being investigated for the treatment of post traumatic stress disorder. The drug has demonstrated clinically significant anxiety reduction in both animal models and in Phase I trials.

CAS Number

160448-56-6 (TFA)

Chemical Formula

C19H24F3N3O5

Molecular Weight

431.4122

Elemental Analysis

C, 52.90; H, 5.61; F, 13.21; N, 9.74; O, 18.54

Synonym

BNC-210; BNC 210; BNC210; IW-2143; IW 2143; IW2143

IUPAC/Chemical Name

(2S)-2-[[(2S,3S)-2-amino-3-methylpentanoyl]amino]-3-(1H-indol-3-yl)propanoic acid trifluoroacetic acid

InChi Key

GIOABCXJJDQJDM-QXGXBFBTSA-N

InChi Code

InChI=1S/C17H23N3O3.C2HF3O2/c1-3-10(2)15(18)16(21)20-14(17(22)23)8-11-9-19-13-7-5-4-6-12(11)13;3-2(4,5)1(6)7/h4-7,9-10,14-15,19H,3,8,18H2,1-2H3,(H,20,21)(H,22,23);(H,6,7)/t10-,14-,15-;/m0./s1

SMILES Code

O=C(O)[C@@H](NC([C@@H](N)[C@@H](C)CC)=O)CC1=CNC2=C1C=CC=C2.O=C(O)C(F)(F)F

Appearance

Solid powder

Purity

>98% (or refer to the Certificate of Analysis)

Shipping Condition

Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.

Storage Condition

Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).

Solubility

To be determined

Shelf Life

>2 years if stored properly

Drug Formulation

To be determined

Stock Solution Storage

0 - 4℃ for short term (days to weeks), or -20℃ for long term (months).

HS Tariff Code

2934.99.9001

All of our services and products are intended for preclinical research use only and cannot be used to diagnose, treat or manage patients.