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BNC-210

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Specification

Cat. No.

SMD145

Related Diseases

Anxiety

Product Name

BNC-210

Size

100.0mg; 200.0mg; 500.0mg; 1.0g; 2.0g

Price

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Availability

2 Weeks

Description

BNC210, also known as IW-2143, is an anxiolytic drug that acts via negative allosteric modulation of the α7-nicotinic acetylcholine receptor. It is currently being investigated for the treatment of post traumatic stress disorder. The drug has demonstrated clinically significant anxiety reduction in both animal models and in Phase I trials.

CAS Number

13589-06-5 (free base)

Chemical Formula

C17H23N3O3

Exact Mass

317.1739

Molecular Weight

317.389

Elemental Analysis

C, 64.33; H, 7.30; N, 13.24; O, 15.12

Synonym

BNC-210; BNC 210 ; BNC210 ; IW-2143; IW 2143; IW2143; H-ILE-TRP-OH; Isoleucyl-Tryptophan;

IUPAC/Chemical Name

(2S)-2-[[(2S,3S)-2-amino-3-methylpentanoyl]amino]-3-(1H-indol-3-yl)propanoic acid

InChi Key

BVRPESWOSNFUCJ-LKTVYLICSA-N

InChi Code

InChI=1S/C17H23N3O3/c1-3-10(2)15(18)16(21)20-14(17(22)23)8-11-9-19-13-7-5-4-6-12(11)13/h4-7,9-10,14-15,19H,3,8,18H2,1-2H3,(H,20,21)(H,22,23)/t10-,14-,15-/m0/s1

SMILES Code

O=C(O)[C@@H](NC([C@@H](N)[C@@H](C)CC)=O)CC1=CNC2=C1C=CC=C2

Appearance

Solid powder

Purity

>98% (or refer to the Certificate of Analysis)

Shipping Condition

Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.

Storage Condition

Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).

Solubility

Soluble in DMSO

Shelf Life

>3 years if stored properly

Drug Formulation

This drug may be formulated in DMSO

Stock Solution Storage

0 - 4℃ for short term (days to weeks), or -20℃ for long term (months).

HS Tariff Code

2934.99.9001

All of our services and products are intended for preclinical research use only and cannot be used to diagnose, treat or manage patients.