Related Diseases
Depression
Description
Binedaline, also known as Scha-1059, Ixprim, binodaline, is a drug that was being investigated as an antidepressant in the 1980s but never marketed. It acts as a selective norepinephrine reuptake inhibitor (Ki = 25 nM), with relatively insignificant influence on the serotonin (Ki = 847 nM) and dopamine (Ki >= 2 µM) transporters. It has negligible affinity for the α-adrenergic, mACh, H1, or 5-HT2 receptors.
Chemical Formula
C19H23N3
Elemental Analysis
C, 77.78; H, 7.90; N, 14.32
Synonym
SCHA-1059; SCHA 1059; SCHA1059; Sgd-Sch-1059; Binedaline; binodaline. Ixprim.
IUPAC/Chemical Name
1-((2-(Dimethylamino)ethyl)methylamino)-3-phenylindole
InChi Key
SXYFFMXPDDGOEK-UHFFFAOYSA-N
InChi Code
InChI=1S/C19H23N3/c1-20(2)13-14-21(3)22-15-18(16-9-5-4-6-10-16)17-11-7-8-12-19(17)22/h4-12,15H,13-14H2,1-3H3
SMILES Code
CN(N1C=C(C2=CC=CC=C2)C3=C1C=CC=C3)CCN(C)C
Purity
>98% (or refer to the Certificate of Analysis)
Shipping Condition
Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
Storage Condition
Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).
Solubility
Soluble in DMSO
Shelf Life
>2 years if stored properly
Drug Formulation
This drug may be formulated in DMSO
Stock Solution Storage
0 - 4℃ for short term (days to weeks), or -20℃ for long term (months).
HS Tariff Code
2934.99.9001