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Bilanafos-sodium

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Specification

Cat. No.

SMD1411

Related Diseases

Schizophrenia

Product Name

Bilanafos-sodium

Size

10.0mg; 50.0mg; 100.0mg

Price

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Availability

2 Weeks

Description

Bialaphos is a natural non-selective phytotoxin produced by certain Streptomyces species. It is a pro-toxin, a tripeptide that is converted in vivo to the active agent phosphinothricin, which is a glutamine analog. L-Phosphinothricin inhibits glutamine synthetase (Ki = 6.1 µM), resulting in accumulation of ammonium and disruption of primary metabolism. The bacterial bar gene encodes a phosphinothricin acetyltransferase, which confers resistance to phosphinothricin.3 Bialaphos is used in the selection of transgenic plants that express the bar gene, usually under the control of a constitutively active viral promoter.

CAS Number

71048-99-2

Chemical Formula

C11H21N3NaO6P

Molecular Weight

345.26

Elemental Analysis

C, 38.27; H, 6.13; N, 12.17; Na, 6.66; O, 27.80; P, 8.97

Synonym

Bilanafos-sodium; MW 801; SF 1293; Bialaphos sodium;

IUPAC/Chemical Name

sodium (2-amino-4-((hydroxymethyl)hydrophosphoryl)butanoyl)-L-alanyl-L-alaninate

InChi Key

ABIKTJOYXWTPDS-NKGRROCASA-M

InChi Code

InChI=1S/C11H22N3O6P.Na/c1-6(9(16)14-7(2)11(18)19)13-10(17)8(12)3-4-21(20)5-15;/h6-8,15,21H,3-5,12H2,1-2H3,(H,13,17)(H,14,16)(H,18,19);/q;+1/p-1/t6-,7-,8?;/m0./s1

SMILES Code

C[C@@H](C([O-])=O)NC([C@H](C)NC(C(N)CCP(CO)=O)=O)=O.[Na+]

Appearance

Solid powder

Purity

>98% (or refer to the Certificate of Analysis)

Shipping Condition

Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.

Storage Condition

Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).

Solubility

Soluble in DMSO

Shelf Life

>2 years if stored properly

Drug Formulation

This drug may be formulated in DMSO

Stock Solution Storage

0 - 4℃ for short term (days to weeks), or -20℃ for long term (months).

HS Tariff Code

2934.99.9001

All of our services and products are intended for preclinical research use only and cannot be used to diagnose, treat or manage patients.