Inquiry

* Name

Phone

* Email

* Services or Products of Interest

Project Description

* Please note that all of our services and products are intended for preclinical research use only and cannot be used to diagnose, treat or manage patients.

* Tick to confirm the Research Use Only (RUO) statement.

Bicuculline

Inquiry

Specification

Cat. No.

SMD126

Related Diseases

Anxiety

Product Name

Bicuculline

Size

50.0mg; 100.0mg; 500.0mg

Price

Inquiry

Availability

2 Weeks

Description

Bicuculline is obtained from Dicentra cucullaria. It is a GABA-A-receptor antagonist and NMDA receptor potentiator used to study GABA signaling. It induces membrane depolarization and prolongs Ca- dependemtn action potentials in neurons.

CAS Number

485-49-4

Chemical Formula

C20H17NO6

Exact Mass

367.1056

Molecular Weight

367.35

Elemental Analysis

C, 65.39; H, 4.66; N, 3.81; O, 26.13

Synonym

Bicculine; Bicucullin; BRN 0098786; NSC 32192; BRN0098786; NSC32192; BRN-0098786; NSC-32192

IUPAC/Chemical Name

(R)-6-((S)-6-methyl-5,6,7,8-tetrahydro-[1,3]dioxolo[4,5-g]isoquinolin-5-yl)-[1,3]dioxolo[4,5-e]isobenzofuran-8(6H)-one

InChi Key

IYGYMKDQCDOMRE-ZWKOTPCHSA-N

InChi Code

InChI=1S/C20H17NO6/c1-21-5-4-10-6-14-15(25-8-24-14)7-12(10)17(21)18-11-2-3-13-19(26-9-23-13)16(11)20(22)27-18/h2-3,6-7,17-18H,4-5,8-9H2,1H3/t17-,18+/m0/s1

SMILES Code

O=C1O[C@@H]([C@H]2N(C)CCC3=CC4=C(OCO4)C=C23)C5=CC=C(OCO6)C6=C51

Appearance

Solid powder

Purity

>98% (or refer to the Certificate of Analysis)

Shipping Condition

Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.

Storage Condition

Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).

Solubility

Soluble in DMSO

Shelf Life

>2 years if stored properly

Drug Formulation

This drug may be formulated in DMSO

Stock Solution Storage

0 - 4℃ for short term (days to weeks), or -20℃ for long term (months).

HS Tariff Code

2934.99.9001

All of our services and products are intended for preclinical research use only and cannot be used to diagnose, treat or manage patients.