Inquiry

* Name

Phone

* Email

* Services or Products of Interest

Project Description

* Please note that all of our services and products are intended for preclinical research use only and cannot be used to diagnose, treat or manage patients.

* Tick to confirm the Research Use Only (RUO) statement.

Balovaptan

Inquiry

Specification

Cat. No.

SMD450

Related Diseases

Autism

Product Name

Balovaptan

Size

Customizable

Price

Inquiry

Description

Balovaptan, also known as RG7314, is a vasopressin receptor antagonist. Balovaptan has shown potential as a treatment for people with autism spectrum disorder (ASD). Balovaptan has shown the potential to improve social interaction and communication in people with ASD. Balovaptan is an investigational small molecule currently in clinical development by Roche for the treatment of ASD. It acts as a vasopressin (V1a) receptor antagonist.

CAS Number

1228088-30-9

Chemical Formula

C22H24ClN5O

Exact Mass

409.1669

Molecular Weight

409.918

Elemental Analysis

C, 64.46; H, 5.90; Cl, 8.65; N, 17.09; O, 3.90

Synonym

RG7314; RG 7314; RG-7314; Balovaptan

IUPAC/Chemical Name

8-chloro-5-methyl-1-{trans-4-[(pyridin-2-yl)oxy]cyclohexyl}-5,6-dihydro-4H-[1,2,4]triazolo[4,3-a][1,4]benzodiazepine

InChi Key

GMPZPHGHNDMRKL-RZDIXWSQSA-N

InChi Code

InChI=1S/C22H24ClN5O/c1-27-13-16-12-17(23)7-10-19(16)28-20(14-27)25-26-22(28)15-5-8-18(9-6-15)29-21-4-2-3-11-24-21/h2-4,7,10-12,15,18H,5-6,8-9,13-14H2,1H3/t15-,18-

SMILES Code

CN1CC2=NN=C([C@H]3CC[C@H](OC4=NC=CC=C4)CC3)[N@]2[C@]5=CC=C(Cl)C=C5C1

Appearance

Solid powder

Purity

>98% (or refer to the Certificate of Analysis)

Shipping Condition

Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.

Storage Condition

Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).

Solubility

Soluble in DMSO

Shelf Life

>2 years if stored properly

Drug Formulation

This drug may be formulated in DMSO

Stock Solution Storage

0 - 4℃ for short term (days to weeks), or -20℃ for long term (months).

HS Tariff Code

2934.99.9001

All of our services and products are intended for preclinical research use only and cannot be used to diagnose, treat or manage patients.