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AZD8926

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AZD8926

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Specification
Cat. No.
SMD1415
Related Diseases
Schizophrenia
Product Name
AZD8926
Size
Customizable
Price
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Description
AZD8926 is a potent and selective GSK3β inhibitor (glycogen synthase kinase-3β). AZD8926 has potential for treating several CNS disorders, such as Alzheimer’s disease (AD), schizophrenia, and chronic as well as acute neurodegenerative diseases.
CAS Number
933785-68-3 (free base)
Chemical Formula
C25H27F4N7O2
Exact Mass
533.2162
Molecular Weight
533.5316
Elemental Analysis
C, 56.28; H, 5.10; F, 14.24; N, 18.38; O, 6.00
Synonym
AZD8926; AZD-8926; AZD 8926.
IUPAC/Chemical Name
(4-((5-fluoro-4-(1-(tetrahydro-2H-pyran-4-yl)-2-(trifluoromethyl)-1H-imidazol-5-yl)pyrimidin-2-yl)amino)phenyl)(4-methylpiperazin-1-yl)methanone
InChi Key
JKLMQKZMMRJQCK-UHFFFAOYSA-N
InChi Code
InChI=1S/C25H27F4N7O2/c1-34-8-10-35(11-9-34)22(37)16-2-4-17(5-3-16)32-24-31-14-19(26)21(33-24)20-15-30-23(25(27,28)29)36(20)18-6-12-38-13-7-18/h2-5,14-15,18H,6-13H2,1H3,(H,31,32,33)
SMILES Code
O=C(C1=CC=C(NC2=NC=C(F)C(C3=CN=C(C(F)(F)F)N3C4CCOCC4)=N2)C=C1)N5CCN(C)CC5
Appearance
Solid powder
Purity
>98% (or refer to the Certificate of Analysis)
Shipping Condition
Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
Storage Condition
Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).
Solubility
Soluble in DMSO, not in water
Shelf Life
>2 years if stored properly
Drug Formulation
This drug may be formulated in DMSO
Stock Solution Storage
0 - 4℃ for short term (days to weeks), or -20℃ for long term (months).
HS Tariff Code
2934.99.9001
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