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AV-101

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Specification

Cat. No.

SMD679

Related Diseases

Depression

Product Name

AV-101

Size

Customizable

Price

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Description

AV-101, also known as 4-Chlorokynurenine; 4-Cl-KYN; AV-101; L-4-Cl-KYN; 4ClKYN; L-4ClKYN, is a NMDA glycine B receptor antagonist potentially for treatment of major depressive disorder. AV-101 is an orally active small molecule prodrug candidate that in vivo produces a glycine binding site NMDA receptor antagonist. AV-101 is in clinical development by VistaGen Therapeutics. Inc. as a potential new generation, fast-acting antidepressant, and for other central nervous system (CNS) indications.

CAS Number

153152-32-0

Chemical Formula

C10H11ClN2O3

Exact Mass

242.0458

Molecular Weight

242.659

Elemental Analysis

C, 49.50; H, 4.57; Cl, 14.61; N, 11.54; O, 19.78

Synonym

AV-101; 4-Cl-KYN; AV-101; L-4-Cl-KYN; 4ClKYN; L-4ClKYN; 4-Chlorokynurenine.

IUPAC/Chemical Name

(2S)-2-Amino-4-(2-amino-4-chlorophenyl)-4-oxobutanoic acid

InChi Key

HQLHZNDJQSRKDT-QMMMGPOBSA-N

InChi Code

InChI=1S/C10H11ClN2O3/c11-5-1-2-6(7(12)3-5)9(14)4-8(13)10(15)16/h1-3,8H,4,12-13H2,(H,15,16)/t8-/m0/s1

SMILES Code

O=C(O)[C@@H](N)CC(C1=CC=C(Cl)C=C1N)=O

Appearance

Solid powder

Purity

>98% (or refer to the Certificate of Analysis)

Shipping Condition

Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.

Storage Condition

Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).

Solubility

Soluble in DMSO

Shelf Life

>2 years if stored properly

Drug Formulation

This drug may be formulated in DMSO

Stock Solution Storage

0 - 4℃ for short term (days to weeks), or -20℃ for long term (months).

HS Tariff Code

2934.99.9001

All of our services and products are intended for preclinical research use only and cannot be used to diagnose, treat or manage patients.