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Atibeprone

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Specification

Cat. No.

SMD665

Related Diseases

Depression

Product Name

Atibeprone

Size

1.0mg; 5.0mg; 10.0mg; 25.0mg; 50.0mg; 100.0mg

Price

Inquiry

Availability

2 Weeks

Description

Atibeprone, also known as Lu 53439, is MAO-B inhibitor. The anticonvulsant activity of inhibitors of monoamine oxidase (MAO) was reported early after the development of irreversible MAO inhibitors such as tranylcypromine, but was never clinically used because of the adverse effects of these compounds. In contrast to esuprone and L-deprenyl, the selective MAO-B inhibitor LU 53439 was not effective in the kindling model; this substantiates the previous notion that the anticonvulsant activity of L-deprenyl is not related to MAO-B inhibition, but to other effects of this drug, such as inhibition of MAO-A.

CAS Number

153420-96-3

Chemical Formula

C17H18N2O3S

Exact Mass

330.1038

Molecular Weight

330.402

Elemental Analysis

C, 61.80; H, 5.49; N, 8.48; O, 14.53; S, 9.70

Synonym

Atibeprone; Lu 53439; Lu-53439; Lu53439;

IUPAC/Chemical Name

7-((5-isopropyl-1,3,4-thiadiazol-2-yl)methoxy)-3,4-dimethyl-2H-chromen-2-one

InChi Key

HQTNJPCZUQAYAB-UHFFFAOYSA-N

InChi Code

InChI=1S/C17H18N2O3S/c1-9(2)16-19-18-15(23-16)8-21-12-5-6-13-10(3)11(4)17(20)22-14(13)7-12/h5-7,9H,8H2,1-4H3

SMILES Code

CC1=C(C)C(OC2=C1C=CC(OCC3=NN=C(C(C)C)S3)=C2)=O

Appearance

Solid powder

Purity

>98% (or refer to the Certificate of Analysis)

Shipping Condition

Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.

Storage Condition

Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).

Solubility

To be determined

Shelf Life

>2 years if stored properly

Drug Formulation

To be determined

Stock Solution Storage

0 - 4℃ for short term (days to weeks), or -20℃ for long term (months).

HS Tariff Code

2934.99.9001

All of our services and products are intended for preclinical research use only and cannot be used to diagnose, treat or manage patients.