Aripiprazole lauroxil

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Aripiprazole lauroxil

Specification
Cat. No.
SMD1384
Related Diseases
Schizophrenia
Product Name
Aripiprazole lauroxil
Size
100.0mg; 200.0mg; 500.0mg; 1.0g; 2.0g; 5.0g
Price
Inquiry
Availability
2 Weeks
Description
Aripiprazole lauroxil, aslo known as RDC 3317, is a long-acting injectable atypical antipsychotic. It is an N-acyloxymethyl prodrug of aripiprazole that is administered via intramuscular injection once every four to six weeks for the treatment of schizophrenia. Aripiprazole lauroxil was approved by the U.S. FDA on 5 October 2015.
CAS Number
1259305-29-7 (lauroxil)
Chemical Formula
C36H51Cl2N3O4
Exact Mass
659.3257
Molecular Weight
660.721
Elemental Analysis
C, 65.44; H, 7.78; Cl, 10.73; N, 6.36; O, 9.69
Synonym
RDC 3317; RDC-3317; RDC3317; ALKS9072; ALKS-9072; ALKS 9072;Aripiprazole lauroxil; Aristada.
IUPAC/Chemical Name
(7-(4-(4-(2,3-dichlorophenyl)piperazin-1-yl)butoxy)-2-oxo-3,4-dihydroquinolin-1(2H)-yl)methyl dodecanoate
InChi Key
DDINXHAORAAYAD-UHFFFAOYSA-N
InChi Code
InChI=1S/C36H51Cl2N3O4/c1-2-3-4-5-6-7-8-9-10-16-35(43)45-28-41-33-27-30(19-17-29(33)18-20-34(41)42)44-26-12-11-21-39-22-24-40(25-23-39)32-15-13-14-31(37)36(32)38/h13-15,17,19,27H,2-12,16,18,20-26,28H2,1H3
SMILES Code
O=C1N(COC(CCCCCCCCCCC)=O)C2=C(C=CC(OCCCCN3CCN(C4=CC=CC(Cl)=C4Cl)CC3)=C2)CC1
Appearance
Solid powder
Purity
>98% (or refer to the Certificate of Analysis)
Shipping Condition
Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
Storage Condition
Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).
Solubility
Soluble in DMSO, not in water
Shelf Life
>2 years if stored properly
Drug Formulation
This drug may be formulated in DMSO
Stock Solution Storage
0 - 4℃ for short term (days to weeks), or -20℃ for long term (months).
HS Tariff Code
2934.99.9001
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