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Arbaclofen placarbil

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Specification

Cat. No.

SMD472

Related Diseases

Autism

Product Name

Arbaclofen placarbil

Size

Customizable

Price

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Description

Arbaclofen placarbil, also known as XP19986, is GABA(B) receptor agonist. Arbaclofen placarbil is a novel R-baclofen prodrug: improved absorption, distribution, metabolism, and elimination properties compared with R-baclofen. Arbaclofen placarbil decreases postprandial reflux in patients with gastroesophageal reflux disease.

CAS Number

847353-30-4

Chemical Formula

C19H26ClNO6

Exact Mass

399.1449

Molecular Weight

399.868

Elemental Analysis

C, 57.07; H, 6.55; Cl, 8.87; N, 3.50; O, 24.01

Synonym

XP19986; XP-19986; XP 19986; Arbaclofen placarbil.

IUPAC/Chemical Name

(R)-3-(4-chlorophenyl)-4-((((S)-1-(isobutyryloxy)-2-methylpropoxy)carbonyl)amino)butanoic acid

InChi Key

JXTAALBWJQJLGN-KSSFIOAISA-N

InChi Code

InChI=1S/C19H26ClNO6/c1-11(2)17(24)26-18(12(3)4)27-19(25)21-10-14(9-16(22)23)13-5-7-15(20)8-6-13/h5-8,11-12,14,18H,9-10H2,1-4H3,(H,21,25)(H,22,23)/t14-,18-/m0/s1

SMILES Code

O=C(O)C[C@H](C1=CC=C(Cl)C=C1)CNC(O[C@H](OC(C(C)C)=O)C(C)C)=O

Appearance

Solid powder

Purity

>98% (or refer to the Certificate of Analysis)

Shipping Condition

Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.

Storage Condition

Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).

Solubility

Soluble in DMSO, not in water

Shelf Life

>2 years if stored properly

Drug Formulation

This drug may be formulated in DMSO

Stock Solution Storage

0 - 4℃ for short term (days to weeks), or -20℃ for long term (months).

HS Tariff Code

2934.99.9001

All of our services and products are intended for preclinical research use only and cannot be used to diagnose, treat or manage patients.