Inquiry

* Name

Phone

* Email

* Services or Products of Interest

Project Description

* Please note that all of our services and products are intended for preclinical research use only and cannot be used to diagnose, treat or manage patients.

* Tick to confirm the Research Use Only (RUO) statement.

Antide acetate

Inquiry

Specification

Cat. No.

SMD089

Related Diseases

Anxiety

Product Name

Antide acetate

Size

1.0mg; 5.0mg; 10.0mg

Price

Inquiry

Availability

2 Weeks

Description

Antide acetate is a third generation gonadotropin-releasing hormone receptor antagonist. It inhibits GnRH-induced secretion of luteinizing hormone, follicle-stimulating hormone, and gonadotropin in isolated rat pituitary cells when used at concentrations ranging from 0.001 to 1,000 nM but does not induce histamine release in isolated rat mast cells. Antide acetate reduces serum LH and FSH levels in orchidectomized cynomolgus monkeys. It inhibits ovulation in rats when administered at a dose of 2 µg/animal. Antide acetate reduces the intensity and duration of catalepsy induced by haloperidol in rats.

CAS Number

625092-10-6

Chemical Formula

C84H112ClN17O16

Exact Mass

1649.8161

Molecular Weight

1651.373

Elemental Analysis

C, 61.10; H, 6.84; Cl, 2.15; N, 14.42; O, 15.50

Synonym

Antide acetate;

IUPAC/Chemical Name

N-((4R,7R,10R,13S,16S,19R)-19-(((S)-1-(((S)-1-((S)-2-(((R)-1-amino-1-oxopropan-2-yl)carbamoyl)pyrrolidin-1-yl)-6-(isopropylamino)-1-oxohexan-2-yl)amino)-4-methyl-1-oxopentan-2-yl)carbamoyl)-7-(4-chlorobenzyl)-13-(hydroxymethyl)-4-(naphthalen-2-ylmethyl)-16-(4-(nicotinamido)butyl)-2,5,8,11,14,17-hexaoxo-10-(pyridin-3-ylmethyl)-3,6,9,12,15,18-hexaazatricosan-23-yl)nicotinamide acetate

InChi Key

RHBDDEILKDGLGU-OHURHHEJSA-N

InChi Code

InChI=1S/C82H108ClN17O14.C2H4O2/c1-50(2)41-65(76(108)95-64(26-11-12-37-88-51(3)4)82(114)100-40-18-27-70(100)81(113)91-52(5)71(84)103)96-75(107)63(25-10-14-39-90-73(105)60-23-17-36-87-48-60)93-74(106)62(24-9-13-38-89-72(104)59-22-16-35-86-47-59)94-80(112)69(49-101)99-79(111)68(45-56-19-15-34-85-46-56)98-78(110)67(43-54-29-32-61(83)33-30-54)97-77(109)66(92-53(6)102)44-55-28-31-57-20-7-8-21-58(57)42-55;1-2(3)4/h7-8,15-17,19-23,28-36,42,46-48,50-52,62-70,88,101H,9-14,18,24-27,37-41,43-45,49H2,1-6H3,(H2,84,103)(H,89,104)(H,90,105)(H,91,113)(H,92,102)(H,93,106)(H,94,112)(H,95,108)(H,96,107)(H,97,109)(H,98,110)(H,99,111);1H3,(H,3,4)/t52-,62+,63-,64+,65+,66-,67-,68-,69+,70+;/m1./s1

SMILES Code

ClC1=CC=C(C[C@H](C(N[C@@H](C(N[C@H](C(N[C@H](C(N[C@@H](C(N[C@H](C(N[C@H](C(N2[C@H](C(N[C@@H](C(N)=O)C)=O)CCC2)=O)CCCCNC(C)C)=O)CC(C)C)=O)CCCCNC(C3=CN=CC=C3)=O)=O)CCCCNC(C4=CN=CC=C4)=O)=O)CO)=O)CC5=CN=CC=C5)=O)NC([C@@H](CC6=CC7=C(C=C6)C=CC=C7)NC(C)=O)=O)C=C1.O=C(O)C

Appearance

Solid powder

Purity

>98% (or refer to the Certificate of Analysis)

Shipping Condition

Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.

Storage Condition

Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).

Solubility

Soluble in DMSO

Shelf Life

>3 years if stored properly

Drug Formulation

This drug may be formulated in DMSO

Stock Solution Storage

0 - 4℃ for short term (days to weeks), or -20℃ for long term (months).

HS Tariff Code

2934.99.9001

All of our services and products are intended for preclinical research use only and cannot be used to diagnose, treat or manage patients.