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Amisulpride free base

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Specification

Cat. No.

SMD1365

Related Diseases

Schizophrenia

Related Diseases

Depression

Related Diseases

Bipolar Disorder

Product Name

Amisulpride free base

Size

50.0mg; 100.0mg; 200.0mg; 500.0mg; 1.0g; 2.0g

Price

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Availability

2 Weeks

Description

Amisulpride is an atypical antipsychotic used to treat psychosis in schizophrenia and episodes of mania in bipolar disorder. In Italy, it is also used as a treatment for dysthymia. It was introduced by Sanofi-Aventis in the 1990s. Its patent had expired by 2008 and hence generic formulations are now available.Amisulpride function primarily as a D2 and D3 receptor antagonist. It has high affinity for these receptors with dissociation constants of 2.2 nM and 2.4 nM, respectively. Although standard doses used to treat psychosis inhibit dopaminergic neurotransmission, low doses preferentially block inhibitory pre-synaptic autoreceptors.

CAS Number

71675-85-9 (free base)

Chemical Formula

C17H27N3O4S

Exact Mass

369.17223

Molecular Weight

369.48

Elemental Analysis

C, 55.26; H, 7.37; N, 11.37; O, 17.32; S, 8.68

Synonym

Solian; Aminosultopride; Deniban; Amisulprida; Amazeo; Amipride; Amival; Soltus; Sulpitac; Sulprix

IUPAC/Chemical Name

4-amino-N-[(1-ethylpyrrolidin-2-yl)methyl]-5-ethylsulfonyl-2-methoxybenzamide

InChi Key

NTJOBXMMWNYJFB-UHFFFAOYSA-N

InChi Code

InChI=1S/C17H27N3O4S/c1-4-20-8-6-7-12(20)11-19-17(21)13-9-16(25(22,23)5-2)14(18)10-15(13)24-3/h9-10,12H,4-8,11,18H2,1-3H3,(H,19,21)

SMILES Code

CCN1CCCC1CNC(=O)C2=CC(=C(C=C2OC)N)S(=O)(=O)CC

Appearance

Solid powder

Purity

>98% (or refer to the Certificate of Analysis)

Shipping Condition

Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.

Storage Condition

Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).

Solubility

Soluble in DMSO, not in water

Shelf Life

>2 years if stored properly

Drug Formulation

This drug may be formulated in DMSO

Stock Solution Storage

0 - 4℃ for short term (days to weeks), or -20℃ for long term (months).

HS Tariff Code

2934.99.9001

All of our services and products are intended for preclinical research use only and cannot be used to diagnose, treat or manage patients.