Related Diseases
Depression
Description
Amibegron is a selective agonist for the β3 adrenergic receptor. It is the first orally active β3 agonist developed that is capable of entering the central nervous system. Amibegron has antidepressant and anxiolytic effects.
Chemical Formula
C22H26ClNO4
Elemental Analysis
C, 65.42; H, 6.49; Cl, 8.78; N, 3.47; O, 15.84
Synonym
Amibegron, SR 58611, SR58611, SR-58611
IUPAC/Chemical Name
Acetic acid, (((7S)-7-(((2R)-2-(3-chlorophenyl)-2-hydroxyethyl)amino)-5,6,7,8- tetrahydro-2-naphthalenyl)oxy)-, ethyl ester
InChi Key
RDJQCOBTKKAQAH-FPOVZHCZSA-N
InChi Code
1S/C22H26ClNO4/c1-2-27-22(26)14-28-20-9-7-15-6-8-19(11-17(15)12-20)24-13-21(25)16-4-3-5-18(23)10-16/h3-5,7,9-10,12,19,21,24-25H,2,6,8,11,13-14H2,1H3/t19-,21-/m0/s1
SMILES Code
[C@H](O)(CN[C@@H]1Cc2cc(ccc2CC1)OCC(=O)OCC)c1cc(ccc1)Cl
Purity
>98% (or refer to the Certificate of Analysis)
Shipping Condition
Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
Storage Condition
Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).
Solubility
Soluble in DMSO
Shelf Life
>3 years if stored properly
Drug Formulation
This drug may be formulated in DMSO
Stock Solution Storage
0 - 4℃ for short term (days to weeks), or -20℃ for long term (months).
HS Tariff Code
2934.99.9001