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Amantadine sulfate

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Specification

Cat. No.

SMD467

Related Diseases

Autism

Related Diseases

Schizophrenia

Product Name

Amantadine sulfate

Size

5.0g; 10.0g; 25.0g

Price

Inquiry

Availability

2 Weeks

Description

Amantadine is a drug that has U.S. Food and Drug Administration approval for use both as an antiviral and an anti-parkinsonian drug. Amantadine is a weak antagonist of the NMDA-type glutamate receptor, increases dopamine release, and blocks dopamine reuptake. Amantadine probably does not inhibit MAO enzyme. Moreover, the mechanism of its antiparkinsonian effect is poorly understood.[citation needed] The drug has many effects in the brain, including release of dopamine and norepinephrine from nerve endings. It appears to be a weak NMDA receptor antagonist as well as an anticholinergic, specifically a nicotinic alpha-7 antagonist like the similar pharmaceutical memantine.

CAS Number

31377-23-8 (sulfate)

Chemical Formula

C20H36N2O4S

Molecular Weight

400.578

Elemental Analysis

C, 59.97; H, 9.06; N, 6.99; O, 15.98; S, 8.00

Synonym

1-Adamantanamine Sulfate;

IUPAC/Chemical Name

Tricyclo(3.3.1.1(3,7))decan-1-amine, sulfate (2:1)

InChi Key

MYWTWSQFJLXGGQ-UHFFFAOYSA-N

InChi Code

InChI=1S/2C10H17N.H2O4S/c2*11-10-4-7-1-8(5-10)3-9(2-7)6-10;1-5(2,3)4/h2*7-9H,1-6,11H2;(H2,1,2,3,4)

SMILES Code

NC1(C2)CC3CC2CC(C3)C1.NC4(C5)CC6CC5CC(C6)C4.O=S(O)(O)=O

Appearance

Solid powder

Purity

>98% (or refer to the Certificate of Analysis)

Shipping Condition

Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.

Storage Condition

Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).

Solubility

Soluble in DMSO

Shelf Life

>2 years if stored properly

Drug Formulation

This drug may be formulated in DMSO

Stock Solution Storage

0 - 4℃ for short term (days to weeks), or -20℃ for long term (months).

HS Tariff Code

2934.99.9001

All of our services and products are intended for preclinical research use only and cannot be used to diagnose, treat or manage patients.