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AL082D06

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Specification

Cat. No.

SMD545

Related Diseases

Bipolar Disorder

Product Name

AL082D06

Size

100.0mg; 200.0mg; 500.0mg; 1.0g; 2.0g; 5.0g

Price

Inquiry

Availability

2 Weeks

Description

AL082D06, also known as D-06, is a nonsteroidal glucocorticoid receptor antagonist. AL082D06 binds specifically to GR with no measurable binding affinity to the progesterone receptor. AL082D06 binds with nanomolar affinity to the GR and has no detectable binding affinity for the highly related receptors for mineralocorticoids, androgens, estrogens, and progestins. AL082D06 inhibits glucocorticoid-mediated transcriptional regulation. AL082D06 binds competitively with steroids, likely occupying a similar site within the ligand-binding domain.

CAS Number

256925-03-8

Chemical Formula

C23H24ClN3O2

Exact Mass

409.1557

Molecular Weight

409.914

Elemental Analysis

C, 67.39; H, 5.90; Cl, 8.65; N, 10.25; O, 7.81

Synonym

AL082D06; AL-082D06; AL 082D06; D-06.

IUPAC/Chemical Name

4,4'-((2-chloro-5-nitrophenyl)methylene)bis(N,N-dimethylaniline)

InChi Key

IPICUXHYPAMJNC-UHFFFAOYSA-N

InChi Code

InChI=1S/C23H24ClN3O2/c1-25(2)18-9-5-16(6-10-18)23(17-7-11-19(12-8-17)26(3)4)21-15-20(27(28)29)13-14-22(21)24/h5-15,23H,1-4H3

SMILES Code

CN(C)C1=CC=C(C(C2=CC=C(N(C)C)C=C2)C3=CC([N+]([O-])=O)=CC=C3Cl)C=C1

Appearance

Solid powder

Purity

>98% (or refer to the Certificate of Analysis)

Shipping Condition

Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.

Storage Condition

Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).

Solubility

Soluble in DMSO, not in water

Shelf Life

>2 years if stored properly

Drug Formulation

This drug may be formulated in DMSO

Stock Solution Storage

0 - 4℃ for short term (days to weeks), or -20℃ for long term (months).

HS Tariff Code

2934.99.9001

All of our services and products are intended for preclinical research use only and cannot be used to diagnose, treat or manage patients.