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ADL5859 HCl

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Specification

Cat. No.

SMD620

Related Diseases

Depression

Product Name

ADL5859 HCl

Size

Customizable

Price

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Description

ADL5859 is a potent, orally bioavailable delta opioid receptor agonist for the treatment of pain ( Ki of 0.8 nM ). ADL5859 agonizes δ-opioid receptor with a 1000-fold selectivity than µ- or κ-opioid receptor with Ki of 32 nM and 37 nM, respectively.

CAS Number

850173-95-4 (ADL 5859 HCl)

Chemical Formula

C24H29ClN2O3

Molecular Weight

428.957

Elemental Analysis

C, 67.20; H, 6.81; Cl, 8.26; N, 6.53; O, 11.19

Synonym

ADL5859; ADL-5859; ADL 5859; ADL5859 HCl.

IUPAC/Chemical Name

N,N-diethyl-4-(5-hydroxyspiro[chromene-2,4'-piperidin]-4-yl)benzamide hydrochloride

InChi Key

ZFNLSWREIULTDO-UHFFFAOYSA-N

InChi Code

InChI=1S/C24H28N2O3.ClH/c1-3-26(4-2)23(28)18-10-8-17(9-11-18)19-16-24(12-14-25-15-13-24)29-21-7-5-6-20(27)22(19)21;/h5-11,16,25,27H,3-4,12-15H2,1-2H3;1H

SMILES Code

O=C(N(CC)CC)C1=CC=C(C2=CC3(CCNCC3)OC4=CC=CC(O)=C24)C=C1.[H]Cl

Appearance

Solid powder

Purity

>98% (or refer to the Certificate of Analysis)

Shipping Condition

Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.

Storage Condition

Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).

Solubility

Soluble in DMSO, not in water

Shelf Life

>2 years if stored properly

Drug Formulation

This drug may be formulated in DMSO

Stock Solution Storage

0 - 4℃ for short term (days to weeks), or -20℃ for long term (months).

HS Tariff Code

2934.99.9001

All of our services and products are intended for preclinical research use only and cannot be used to diagnose, treat or manage patients.