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Adipiplon

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Specification

Cat. No.

SMD1297

Related Diseases

Insomnia

Product Name

Adipiplon

Size

Customizable

Price

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Description

Adipiplon, also known as NG2-73 or NG273, is a new, selective gamma-amino butyric acid (GABA) partial agonist under development for the treatment of insomnia, the most common type of sleep disorder. Phase II development initial clinical results suggested that NG2-73 has the capacity to reduce sleep latency as well as increase total sleep time and sleep efficiency in insomnia patients.

CAS Number

840486-93-3

Chemical Formula

C18H18FN7

Exact Mass

351.1608

Molecular Weight

351.3894

Elemental Analysis

C, 61.53; H, 5.16; F, 5.41; N, 27.90

Synonym

NG2-73; NG 2-73; NG-2-73; NG273; NG 273; NG-273; Adipiplon

IUPAC/Chemical Name

7-((2-(3-fluoropyridin-2-yl)-1H-imidazol-1-yl)methyl)-2-methyl-8-propyl-[1,2,4]triazolo[1,5-c]pyrimidine

InChi Key

UAMAIHOEGLEXSV-UHFFFAOYSA-N

InChi Code

InChI=1S/C18H18FN7/c1-3-5-13-15(22-11-26-17(13)23-12(2)24-26)10-25-9-8-21-18(25)16-14(19)6-4-7-20-16/h4,6-9,11H,3,5,10H2,1-2H3

SMILES Code

CCCC1=C(CN2C=CN=C2C3=NC=CC=C3F)N=CN4C1=NC(C)=N4

Appearance

Solid powder

Purity

>98% (or refer to the Certificate of Analysis)

Shipping Condition

Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.

Storage Condition

Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).

Solubility

Soluble in DMSO, not in water

Shelf Life

>2 years if stored properly

Drug Formulation

This drug may be formulated in DMSO

Stock Solution Storage

0 - 4℃ for short term (days to weeks), or -20℃ for long term (months).

HS Tariff Code

2934.99.9001

All of our services and products are intended for preclinical research use only and cannot be used to diagnose, treat or manage patients.