Ace Therapeutics offers comprehensive acute and chronic toxicity assessment services to clients in the field of antipsychotic drug development. Our technical team is highly experienced in toxicology and drug safety evaluation, and is dedicated to providing comprehensive solutions and toxicological data to accelerate the antipsychotic drug development process.

Overview of Acute and Chronic Toxicity Assessment Services for Antipsychotics

The acute and chronic toxicity assessment service for antipsychotic drugs is a comprehensive safety assessment program designed to evaluate the potential risks associated with drug candidates. This program involves exposing the drug to be tested to experimental animals on a short- or long-term basis.

• The acute toxicity test is designed to assess the immediate toxic effects of a single or multiple doses over a short period of time. This includes monitoring changes in the behavior and signs of the animals.
• The chronic toxicity testing is concerned with evaluating the long-term, cumulative effects of a drug in animals following continuous administration over an extended period. The long-term toxicity of the drug to different organs is evaluated through observation of pathological and physiological changes in animals under the influence of the drug.

Our rigorous experimental design and comprehensive toxicity assessment services provide the necessary safety data for the development of antipsychotic drugs.

Our Capabilities

• Acute toxicity assessment

In acute toxicity testing, we typically utilize in vitro cellular models and animal experiments to assess the immediate toxic effects of potential antipsychotic drugs on biological systems. Our services include measuring the drug's effects on cell viability, cytotoxicity, acute toxicity effects, and behavioral and cosmetic changes in animals. Our acute toxicity data can assist you in making informed decisions in the following areas:

• Toxic effects and intensity of drug candidates.
• To understand the toxic target organs of drug candidates.
• To provide reference for long term toxicity, dosage design for specific toxicity tests.
• To provide reference for clinical toxicity studies and monitoring.

• Chronic toxicity assessment

In chronic toxicity assessments, we typically utilize rodents for long-term drug exposure studies. The frequency of exposure is typically once a day, but the frequency of administration and the period of administration may vary depending on the route chosen and can be modified according to the toxicokinetic profile of the drug to be tested. We assess the long-term safety and potential side effects of drugs by examining their effects on body weight changes, organ function, and histopathology in animals.

Advantages of Ace Therapeutics

• Professional team composed of senior toxicologists, pathologists, biostatisticians, etc.
• We provide customized toxicological evaluation programs according to customer needs and drug properties.
• We will provide the detailed experimental data and final experimental reports within the agreed timeframe.

Ace Therapeutics is dedicated to providing a comprehensive suite of acute and chronic toxicity assessment solutions to assist researchers and developers in understanding the potential risks of their antipsychotic drug candidates and in obtaining the scientific data necessary to support clinical trials and drug launches. If you are interested in our services or require further information, please feel free to contact us.