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ACPT-1

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Specification

Cat. No.

SMD653

Related Diseases

Depression

Product Name

ACPT-1

Size

5.0mg; 10.0mg

Price

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Availability

2 Weeks

Description

ACPT-1 is a blood-brain barrier permeable agonist of group III metabotropic glutamate (mGlu) receptors. In primary neuronal cell cultures ACPT-I (1-200 μM), applied 30 min-3 h after starting the exposure to KA (150 μM), significantly attenuated the KA-induced LDH release, increased cell viability, and inhibited caspase-3 activity both in cortical and hippocampal cell cultures.

CAS Number

194918-76-8

Chemical Formula

C8H11NO6

Exact Mass

217.0586

Molecular Weight

217.17

Elemental Analysis

C, 44.24; H, 5.11; N, 6.45; O, 44.20

Synonym

ACPT-1; ACPT 1; ACPT1;

IUPAC/Chemical Name

(1S,3R,4S)-1-aminocyclo-pentane-1,3,4-tricarboxylic acid

InChi Key

FERIKTBTNCSGJS-KIGHRTHISA-N

InChi Code

InChI=1S/C8H11NO6/c9-8(7(14)15)1-3(5(10)11)4(2-8)6(12)13/h3-4H,1-2,9H2,(H,10,11)(H,12,13)(H,14,15)/t3-,4+,8-

SMILES Code

O=C([C@@]1(N)C[C@@H](C(O)=O)[C@@H](C(O)=O)C1)O

Appearance

Solid powder

Purity

>98% (or refer to the Certificate of Analysis)

Shipping Condition

Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.

Storage Condition

Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).

Solubility

Soluble in DMSO

Shelf Life

>3 years if stored properly

Drug Formulation

This drug may be formulated in DMSO

Stock Solution Storage

0 - 4℃ for short term (days to weeks), or -20℃ for long term (months).

HS Tariff Code

2934.99.03.00

All of our services and products are intended for preclinical research use only and cannot be used to diagnose, treat or manage patients.