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ABT-107

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ABT-107

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Specification
Cat. No.
SMD1390
Related Diseases
Schizophrenia
Related Diseases
Anxiety
Product Name
ABT-107
Size
Customizable
Price
Inquiry
Description
ABT-107 is an α7 nicotinic receptor agonist. ABT-107 strongly suppressed the activation of NF-κB in progranulin-deficient cells. Treatment with ABT-107 also reduced microgliosis, decreased TNFα levels, and reduced compulsive behavior in progranulin-deficient mice.
CAS Number
855291-54-2
Chemical Formula
C19H20N4O
Exact Mass
320.1637
Molecular Weight
320.396
Elemental Analysis
C, 71.23; H, 6.29; N, 17.49; O, 4.99
Synonym
ABT-107; ABT107; ABT 107;
IUPAC/Chemical Name
3-((6-(1H-indol-5-yl)pyridazin-3-yl)oxy)quinuclidine
InChi Key
LUKNJAQKVPBDSC-UHFFFAOYSA-N
InChi Code
InChI=1S/C19H20N4O/c1-2-16-15(5-8-20-16)11-14(1)17-3-4-19(22-21-17)24-18-12-23-9-6-13(18)7-10-23/h1-5,8,11,13,18,20H,6-7,9-10,12H2
SMILES Code
N12CCC(C(OC3=NN=C(C4=CC5=C(NC=C5)C=C4)C=C3)C2)CC1
Appearance
Solid powder
Purity
>98% (or refer to the Certificate of Analysis)
Shipping Condition
Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
Storage Condition
Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).
Solubility
To be determined
Shelf Life
>2 years if stored properly
Drug Formulation
To be determined
Stock Solution Storage
0 - 4℃ for short term (days to weeks), or -20℃ for long term (months).
HS Tariff Code
2934.99.9001
All of our services and products are intended for preclinical research use only and cannot be used to diagnose, treat or manage patients.

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