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ABT-107

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Specification

Cat. No.

SMD1390

Related Diseases

Schizophrenia

Related Diseases

Anxiety

Product Name

ABT-107

Size

Customizable

Price

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Description

ABT-107 is an α7 nicotinic receptor agonist. ABT-107 strongly suppressed the activation of NF-κB in progranulin-deficient cells. Treatment with ABT-107 also reduced microgliosis, decreased TNFα levels, and reduced compulsive behavior in progranulin-deficient mice.

CAS Number

855291-54-2

Chemical Formula

C19H20N4O

Exact Mass

320.1637

Molecular Weight

320.396

Elemental Analysis

C, 71.23; H, 6.29; N, 17.49; O, 4.99

Synonym

ABT-107; ABT107; ABT 107;

IUPAC/Chemical Name

3-((6-(1H-indol-5-yl)pyridazin-3-yl)oxy)quinuclidine

InChi Key

LUKNJAQKVPBDSC-UHFFFAOYSA-N

InChi Code

InChI=1S/C19H20N4O/c1-2-16-15(5-8-20-16)11-14(1)17-3-4-19(22-21-17)24-18-12-23-9-6-13(18)7-10-23/h1-5,8,11,13,18,20H,6-7,9-10,12H2

SMILES Code

N12CCC(C(OC3=NN=C(C4=CC5=C(NC=C5)C=C4)C=C3)C2)CC1

Appearance

Solid powder

Purity

>98% (or refer to the Certificate of Analysis)

Shipping Condition

Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.

Storage Condition

Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).

Solubility

To be determined

Shelf Life

>2 years if stored properly

Drug Formulation

To be determined

Stock Solution Storage

0 - 4℃ for short term (days to weeks), or -20℃ for long term (months).

HS Tariff Code

2934.99.9001

All of our services and products are intended for preclinical research use only and cannot be used to diagnose, treat or manage patients.