Why Is Hyperopia?

Hyperopia is an ocular refractive error that causes blurred vision when viewing objects at close distances. Clinical manifestations include difficulty seeing objects at close range, cross-eyed children, and blurred vision. Although the mechanisms linking refractive error and ocular complications are poorly understood. However, it is widely believed that hyperopia's general structural features play a causal role. For example, a shorter axial length in hyperopia may result in abnormal anterior structures, increasing the risk of angle-closure glaucoma. Therefore, ideal hyperopia models are urgently needed to study this sight-threatening disease.

Service Overview

Ace Therapeutics is a developer and supplier of innovative ocular diseases, and here we are pleased to offer chicken hyperopia models to advance your projects.

At Ace Therapeutics, our researchers use defocused, positive power lenses to blur central vision in chicks, or exposed chicks to continuous light or increased light intensity to induce hypermetropia.

Additionally, our researchers also explore the induction of progressive hyperopia by rearing chicks under blue light. These models have been verified by a large number of experiments and show obvious hyperopia characteristics.

Fascinating to our clients, our chick hyperopia model provide new insights into the cellular and molecular mechanisms of growth control and has been widely used to identify potential new targets for drug development and the treatments needed to stem the rising prevalence of hypermetropia and the sight-threatening conditions associated with the disease.

Available Support Services

In order to quickly and accurately measure the axial length and other eye dimensions of chicks, and test the effect of preventive hyperopia therapy, our researchers use spectral domain optical coherence tomography to measure the following indexes, including but not limited to:

• Axial length
• Focal length
• Lens diameter
• Retinal radius

In addition, we also provide refraction and ultrasonography, retinal molecular biology analysis, and many other services. What attracts our partners is that our services cover the entire preclinical research process. Our team of experts will accompany you throughout the process to smoothly advance your project to the next stage.

Ace Therapeutics aims to provide a powerful analytical tool to help our global customers explore the mechanism of hyperopia and screen drug candidates to control myopia and prevent its development. If you are interested in our services or need more detailed information, please feel free to contact us. Our experienced scientists are ready to help you!

References

1. Wisely CE, Sayed JA, Tamez H, et al. The chick eye in vision research: An excellent model for the study of ocular disease. Prog Retin Eye Res. 2017, 61:72-97.
2. Foulds WS, Barathi VA, Luu CD. Progressive myopia or hyperopia can be induced in chicks and reversed by manipulation of the chromaticity of ambient light. Invest Ophthalmol Vis Sci. 2013, 54(13):8004-12.

• Customized Chicken Models of Myopia
• Customized Chicken Models of Inherited Eye Disease
• Customized Chicken Models of Retinal Injury
• Customized Chick Embryo Models of Uveal Melanoma
• Customized Chicken Models of Corneal Wound Healing

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