Ocular Drug Delivery Introduction

Ocular drug delivery remains a significant challenge in the presence of various ocular barriers that are specific depending on the route of administration, such as topical, systemic, and injection. Major barriers include static barriers imposed by the cornea, conjunctiva, and retinal pigment epithelium, and dynamic barriers including tear turnover and blood and lymphatic clearance mechanisms. In addition to rapid vascular clearance mechanisms, systemic administration by oral and parenteral routes is limited by static blood tissue barriers including epithelial and endothelial layers. Together, static and dynamic barriers limit the rate and extent of drug delivery to the eye.

Fig. 1. Routes of drug administration to eye. (Moshiri A, et al., 2021)

Service Overview

Ace Therapeutics is a biotechnology company specializing in preclinical ophthalmology research. We can help researchers worldwide examine the efficacy of novel test drugs and treatment modes. With years of experience in visual research, our researchers can not only help you choose an appropriate ocular disease model and design and develop a customized experimental protocol but also determine the best route of administration according to the characteristics of your product, for example, vitreous injection, subretinal injection, anterior chamber injection, local administration, systemic administration, etc.

Ace Therapeutics is pleased to provide you with comprehensive ocular dosing services, which are parallel to our ocular disease models to meet your project needs.

Based on our high-quality comprehensive ocular dosing services, our talented expert team has designed and developed various traditional and emerging drug delivery systems with our partners, such as emulsions, ointments, liposomes, dendrimers, nanoparticles, etc.

Access Ace Therapeutics' Comprehensive Ocular Dosing Services

Ace Therapeutics provides the following comprehensive ocular dosing services for global customers' ophthalmic product efficacy testing, including but not limited to:

Advantages of Ace Therapeutics' Comprehensive Ocular Dosing Services

• Supporting multiple eye diseases and species models.
• Experienced ocular drug delivery researchers ensure a high success rate.
• A series of supplementary services.
• The most economical and most suitable ocular drug delivery method was chosen for customer project needs.

Thanks to extensive experience in the field of ocular drug delivery. Ace Therapeutics is pleased to share our best-in-class technology and advanced comprehensive ocular dosing services with global customers. If you are interested in our services or need more detailed information, please feel free to contact us. Our experienced scientists are ready to help you!

Reference

1. Gaudana R, Ananthula HK, Parenky A, et al. Ocular drug delivery. AAPS J. 2010, 12(3):348-60.

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