Ace Therapeutics is an expert in the field of liver disease. We aim to provide the most advanced and comprehensive drug development services to liver disease investigators.
Compared with small molecule chemical drugs, recombinant proteins have the advantages of more significant efficacy, greater specificity, lower toxicity, fewer side effects, and more defined biological functions. Recombinant proteins have an irreplaceable role in disease treatment. Current studies have shown that recombinant protein drugs have significant therapeutic effects in cirrhosis, alcoholic liver disease, fatty liver disease, and other liver diseases. We offer a comprehensive service to support recombinant protein drugs for the treatment of liver diseases.
What Can We Do?
In view of the promising therapeutic results of recombinant proteins such as recombinant human cytoglobin and recombinant nAG protein in liver disease research, we provide comprehensive services in the field of recombinant protein drug development targeting the liver disease. Based on our professional team and advanced platform, we are confident to provide you with the highest quality recombinant protein drug development services.
- Recombinant Protein Drugs Development for Liver Disease
Recombinant protein drugs are a new type of drug with the advantages of greater efficacy, greater specificity, lower toxicity, and more defined biological functions. We provide comprehensive development services for recombinant protein drugs with therapeutic effects in liver diseases.
- We have extensive research experience in the field of protein expression and can provide you with different protein expression systems. For recombinant protein drugs, we even provide suitable mammalian cell expression systems to obtain high-quality recombinant proteins.
- We provide experimental models of different liver diseases to evaluate the effects of recombinant protein drugs from both in vitro and in vivo perspectives.
- We have comprehensively examined the extent of liver disease damage and the effect of drug candidates from the perspective of biomarkers and pathological tests of liver injury.
- Optimization of Recombinant Protein Drugs
Large molecule protein drugs tend to have short half-life, single route of administration, immunogenicity, and toxic side effects. These problems are also the main reasons that hinder the application of recombinant protein drugs. For this purpose, we offer a comprehensive service for the optimization of recombinant protein drugs.
- Chemical Modification
We covalently couple protein drugs with macromolecular hydrophilic modifiers to improve the performance of recombinant protein drugs by covalent modifications. Commonly used methods include polyethylene glycol modification, polysialic acid modification, fatty acid modification, etc.
- Constructing Mutants
We will construct mutants to improve the stability of the protein by mutating sites in the protein molecule, thereby increasing the affinity and activity of the protein and effectively prolonging the duration of drug action.
- Protein Fusions
We have extensive research experience in protein fusion. We can provide Fc fusion protein, human serum albumin fusion protein, and other methods to obtain long-acting recombinant protein drugs.
- Glycosylation
Using the effect of sugar chains on the protein surface on protein activity, we use carbonylation technology to improve the activity of recombinant proteins and effectively enhance their efficacy.
Based on our research experience in the field of liver disease research, Ace Therapeutics is committed to providing you with the highest quality services. We are proud to be able to solve your problems. If you would like to learn more about our services, please feel free to contact us.
Related Services
Our products and services are for research use only and can not be used for diagnostic or other purposes.
