Ace Therapeutics has extensive research experience in the field of liver disease drug development. We aim to provide a one-stop drug development platform for liver disease drug developers worldwide.
As natural compounds are intensively researched, more and more natural compounds are showing therapeutic effects on liver disease. These natural compounds can be used in a variety of ways including antioxidant, anti-inflammatory, and protective effects for the treatment of liver disease. We aim to provide the most comprehensive drug development services for different natural compounds with therapeutic potential for liver disease to support your drug development research.
What Can We Do?
Natural compounds are a vast treasure trove of promising drug candidates. We offer a comprehensive research service for the therapeutic potential of different natural compounds for liver disease.
- Flavonoid Drug Development for Liver Disease Treatment
In view of the currently identified activity of flavonoids in the treatment of liver disease, we offer comprehensive services for the detection of activity and evaluation of therapeutic effects against liver disease.
- For the regulation of intestinal flora by flavonoids, we offer exclusive services, including but not limited to
We will examine the effect of flavonoid compounds on the organism's intestinal flora by 16S RNA, fluorescent quantitative PCR, and other techniques.
We will examine the effect of flavonoid compounds on intestinal barrier function by intestinal permeability assay, plasma diamine oxidase activity assay, and intestinal bacterial translocation.
We will combine metabolomics and microbiomics techniques to detect the effects of flavonoid compounds on the levels of bacterial metabolites.
- For the regulation of oxidative stress by flavonoids, we offer exclusive services, including but not limited to
We will examine antioxidant enzymes and indicators of reactive oxygen species to assess the effect of flavonoids on oxidative stress in the course of liver disease.
We will examine oxidative stress-related signaling pathways to assess the effect of flavonoids on the body's ability to resist oxidative stress.
In addition, for the anti-inflammatory effect of flavonoids, we will assay typical inflammatory pathways and cytokines by PCR, western blotting, and other assays to evaluate their therapeutic effect on liver disease.
- Terpenoids Drug Development for Liver Disease Treatment
Given the multiple activities of terpenoids, we offer comprehensive research services to develop terpene drug candidates for liver disease, including but not limited to
- Given that many terpenoids have significant hepatoprotective effects, we will comprehensively evaluate the hepatoprotective effects of the drug candidates by examining the effects of terpenoids on hepatocyte regeneration, hepatic lipid peroxidation, and other processes.
- Since terpenoids can effectively inhibit endoplasmic reticulum stress, we will screen endoplasmic reticulum stress-related genes by gene microarray technology to further investigate the mechanism of action of terpenoids in treating liver disease by inhibiting endoplasmic reticulum stress.
- In view of the inhibitory effect of terpenoids on apoptosis, we will comprehensively evaluate the therapeutic effect of terpenoids on the liver disease through inhibition of apoptosis by morphological examination, phosphatidylserine exocytosis analysis, and detection of mitochondrial membrane potential and DNA fragmentation assay.
Ace Therapeutics has extensive research experience in the field of natural drug development for liver diseases. Based on our professional scientists and rich practical experience, we aim to provide you with the most professional drug development services. If you would like to learn more about our services, please feel free to contact us.
Related Services
Our products and services are for research use only and can not be used for diagnostic or other purposes.
