Ace Therapeutics is an expert in the field of liver disease research. We have extensive research experience in the field of therapeutic mitochondrial transplantation.
Mitochondrial transplantation therapy is a powerful treatment for liver disease. However, the modality of mitochondrial transplantation is also critical in determining the effectiveness of mitochondrial transplantation. The two main types of mitochondrial transplantation therapies currently used are in vitro and in vivo transplantation. We provide a comprehensive research service to support the development of mitochondrial transplantation therapies for these two types of approaches.
What Can We Do?
The mitochondrial transplantation method has an important impact on the efficacy of mitochondrial transplantation. Our scientists have optimized and developed mitochondrial transplantation modalities from both in vitro and in vivo perspectives to facilitate the progress of related research.
- In vitro Transplantation Method
There are different methods of in vitro transplantation and we have established a mature service plan and process for different methods of in vitro transplantation.
- We can provide microinjection techniques to transfer mitochondria directly into cultured cells.
- We can perform the cell-mediated transfer using tunneling nanotubes.
- We can perform the exogenous mitochondrial transfer using the co-incubation of cultured cells with mitochondria.
- In vivo Transplantation Method
In vivo transplantation of mitochondria is capable of being taken into multiple organs and tissues, which may have a more beneficial effect in some diseases, such as hereditary mitochondrial myopathies. We have explored different methods of in vivo mitochondrial transplantation and have established a stable service protocol.
- We can perform in vivo mitochondrial transplantation by direct injection technique.
- Given the intercellular transfer of mitochondria in vivo, we have developed well-established methods to induce mitochondrial transfer.
- Optimization of Transplantation Method
We offer a range of services to further characterize and optimize the transplantation pathway and graft results.
- We can determine the presence of exogenous mtDNA by performing PCR assays against exogenous mitochondrial mtDNA.
- We can customize mitochondria containing chloramphenicol resistance specific sequences and transfer them.
- We can develop species-specific mitochondrial antibodies for you to detect exogenous mitochondria.
- We have mitochondria from different sources and can perform comparison and optimization of the transplantation effect of endogenous and exogenous mitochondria.
- We offer different liver disease models to evaluate the efficacy of different mitochondrial transplantation modalities for the treatment of liver disease.
Based on our extensive hands-on experience, the scientists at Ace Therapeutics are committed to delivering the best research services in mitochondrial transplantation therapy to our clients worldwide. If you would like to learn more about our services, please feel free to contact us.
Our products and services are for research use only and can not be used for diagnostic or other purposes.
