Ace Therapeutics provides comprehensive research services to liver cancer researchers worldwide. Our professional team will customize the right service plan for you based on your project needs.
The pathogenesis of liver cancer is intricate and closely related to multiple physiological and pathological processes. The specific pathological mechanisms are not yet fully understood. Therefore, we provide comprehensive exploration services for different pathogenesis of liver cancer to save valuable time and effort for your research project, while promoting the progress of liver cancer research.
Fig.1 A two-stage model of HCC development. (Pan, H., et al., 2011)
What Can We Do?
The development of liver cancer is associated with many pathological processes, but there is still a lack of in-depth research on these pathological mechanisms. We facilitate the research progress of your liver cancer program by providing a comprehensive discovery service.
- Inflammation & Liver Cancer
Liver cancer usually develops on the basis of liver inflammation, and inflammation further promotes the pathological process of liver cancer. We provide a comprehensive research service to explore the role of inflammatory pathways in liver cancer.
- Given the regulatory role of inflammatory signaling pathways in liver cancer, we will perform comprehensive exploration services targeting inflammation-related signaling pathways, such as NFκB, STAT3, IL-6, JNK, and other signaling pathways.
- Given the role that activation of innate immune receptors, such as Toll-like receptors and damage-related molecules, plays in hepatocarcinogenesis, we will explore the role of TLR4, MyD88, Nanog, and others in regulating liver cancer through inflammation.
- Given that changes in the metabolic phenotype of hepatocytes are one of the major changes in the early stages of liver cancer, we will delve into the relationship between liver cancer and metabolic disorders, including metabolite accumulation and even metabolic dysfunction.
- For different genes and proteins, we will provide appropriate assays such as qPCR, Northern blot, fluorescence in situ hybridization, WB, ELISA, flow cytometry, immunohistochemistry, luciferase reporter system, and other experiments according to your research project.
- Liver Repair & Liver Cancer
The liver has a unique ability to repair, but irregular regeneration of the liver leads to the continuous proliferation of hepatocytes, which in turn promotes the development of liver cancer. We provide well-established research services to address the role of the liver's repair capacity in liver cancer.
- Given the important role of cytokines, growth factors, and metabolic signals in liver repair, we will perform a comprehensive screening of relevant pathways by gene microarray technology and protein microarray technology to identify specific targets.
- Farnesoid X Receptor (FXR) is an essential regulator of liver repair, with activities such as negative regulation of bile acid synthesis, regulation of bile acid efflux, regulation of lipid metabolism, and glucose metabolism. We will provide different assays to explore the regulatory role of FXR in hepatocellular carcinoma.
Ace Therapeutics offers comprehensive exploration services targeting the role of epigenetics, gut microbiome, chemokines, non-coding RNAs, and other pathological mechanisms in the regulation of liver cancer. Our team develops the right service protocols for you based on your needs. If you would like to learn more about our services, please feel free to contact us.
Reference
- Pan, H., et al., Molecular mechanism of liver cancer. Anticancer Agents Med Chem, 2011. 11(6): p. 493-499.
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Our products and services are for research use only and can not be used for diagnostic or other purposes.
