WYE-354

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Cat. No.: DIA-0230044

Size: 50 mg Size: 500 mg Size: Customer Size

Product Information
CAS No.	1062169-56-5
Formula	C₂₄H₂₉N₇O₅
Molecular Weight	495.53
SMILES	COC(=O)NC1=CC=C(C=C1)C2=NC3=C(C=N[N]3C4CCN(CC4)C(=O)OC)C(=N2)N5CCOCC5
Target	mTOR
Product Description	WYE-354 is a potent, specific and ATP-competitive inhibitor of mTOR with IC50 of 5 nM, blocks mTORC1/P-S6K(T389) and mTORC2/P-AKT(S473) not P-AKT(T308), selective for mTOR than PI3Kα (>100-fold) and PI3Kγ (>500-fold).

Format & Storage
Purity	> 97%
Shipping	Shipped on dry ice.
Storage	Powder: -20 °C, 3 years; 4 °C, 2 years In solvent: -80 °C, 6 months; -20 °C, 1 month
Solubility Overview	Soluble in DMSO

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