VU-0361737

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Cat. No.: DIA-0230069

Size: 50 mg Size: 500 mg Size: Customer Size

Product Information
CAS No.	1161205-04-4
Formula	C₁₃H₁₁ClN₂O₂
Molecular Weight	262.69
SMILES	COC1=CC(=CC=C1Cl)NC(=O)C2=NC=CC=C2
Product Description	VU 0361737 is a selective positive allosteric modulator (PAM) for mGlu4 receptor with EC50 of 240 nM and 110 nM at human and rat receptors, respectively, displays weak activity at mGlu5 and mGlu8 receptors, is inactive at mGlu1, mGlu2, mGlu3, mGlu6 and mGlu7 receptors, can penetrate into CNS.

Format & Storage
Purity	> 98%
Shipping	Shipped on dry ice.
Storage	Powder: -20 °C, 3 years; 4 °C, 2 years In solvent: -80 °C, 6 months; -20 °C, 1 month
Solubility Overview	Soluble in DMSO

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