Vemurafenib (PLX4032, RG7204)

Vemurafenib (PLX4032, RG7204)

Cat. No.: DIA-0230094

Size: 50 mg Size: 500 mg Size: Customer Size
Product Information
CAS No. 918504-65-1
Synonyms RO5185426
Formula C23H18ClF2N3O3S
Molecular Weight 489.92
SMILES CCC[S](=O)(=O)NC1=CC=C(F)C(=C1F)C(=O)C2=C[NH]C3=NC=C(C=C23)C4=CC=C(Cl)C=C4
Product Description Vemurafenib (PLX4032, RG7204) is a novel and potent inhibitor of B-RafV600E with IC50 of 31 nM in cell-free assay. 10-fold selective for B-RafV600E over wild-type B-Raf in enzymatic assays and the cellular selectivity can exceed 100-fold.
Format & Storage
Purity > 98%
Shipping Shipped on dry ice.
Storage Powder: -20 °C, 3 years; 4 °C, 2 years In solvent: -80 °C, 6 months; -20 °C, 1 month
Solubility Overview Soluble in DMSO
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