Generally, there are two scenarios you want to perform a drug identification analysis. The first scenario is you "have a drug of efficacy but the target is unknown". The other is you "need to find a target for new drug discovery and development". Whether you are performing studies on antibody therapy, insulin alternatives or other treatments about diabetes, Ace Therapeutics can provide a full range of services related to diabetes.
When you need to find a target for new drug discovery and development, target identification is also known as target discovery, where a druggable target needs to be established before drug screening. A gene or a biomarker with known functions in diabetes process is identified to generate drug screening assays.
Use of Epigenetic Profiling of Progenitor Cells and Mature β-cells in Diabetes Research (Nuria, C. B.; et al. Trends in Endocrinology & Metabolism, 2012)
When you have a drug of efficacy but the target is unknown, target identification is also known as target deconvolution, where the determination of the small molecular target is after the drug has been proved to exert the desired effect. Phenotypic discovery is a mechanistic agnostic strategy. Therapeutics are identified by the effect upon a phenotype and subsequently the newly identified therapeutics are used to identify the mechanism of action.
Target Identification and Validation is A Multifunctional Process
It is an extremely important part of the drug development stage to identify and validation the target, confirm the importance of its physiology and pathology. Ace Therapeutics has the expertise, scale and instruments to provide the target identification services. Our services include but not limited to the followings.
We offer strategies to identify new genes or proteins targets and verify whether the genes or proteins of interest are targets for diabetic therapy development.
We are able to identify the molecular target(s) of a drug with unknown/uncertain targets but known/certain efficacy.
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Ace Therapeutics can accelerate the therapeutic development and drug discovery process about diabetes for our clients worldwide. Our assays are developed and processed with the highest standard and the results are delivered on time without compromising quality. Please feel free to contact us.
