Streptozotocin-induced (STZ) Rat

Streptozotocin-induced (STZ) Rat

Cat. No.: DMM-001002

Status Age Sex
  • Live Mouse
  • Frozen Embryo
  • 4 weeks
  • 12 weeks
  • Customized Age
  • Male
  • Female
Product Overview
Model Description This knockout mutant of the Pdcd4 (programmed cell death 4) gene exhibits reduced cytokine secretion, lower susceptibility to LPS challenge and EAE, resistance to STZ- induced diabetes, and develops spontaneous lymphoma.
Strain Name B6.129S6-Pdcd4tm1Yhcn/J
Background Strain B6.129S6
SPF Yes
Genetic Modification Conventional knockout
Research Application Diabetes
Target Information
Target Name Pdcd4
Synonyms Programmed cell death 4
Gene ID 27250
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