Streptozotocin-induced (STZ) Rat

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Streptozotocin-induced (STZ) Rat

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Cat. No.: DMM-001002

Status	Age	Sex
Live Mouse Frozen Embryo	4 weeks 12 weeks Customized Age	Male Female

Product Overview
Model Description	This knockout mutant of the Pdcd4 (programmed cell death 4) gene exhibits reduced cytokine secretion, lower susceptibility to LPS challenge and EAE, resistance to STZ- induced diabetes, and develops spontaneous lymphoma.
Strain Name	B6.129S6-Pdcd4^tm1Yhcn/J
Background Strain	B6.129S6
SPF	Yes
Genetic Modification	Conventional knockout
Research Application	Diabetes

Target Information
Target Name	Pdcd4
Synonyms	Programmed cell death 4
Gene ID	27250

All of our services and products are intended for preclinical research use only and cannot be used to diagnose, treat or manage patients.

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Ace Therapeutics has a team of experts in the field of endocrine and metabolic research, aiming to provide innovative preclinical contract research solutions to cope with diabetes and its complications. We provide customized solutions and technical support, enabling the transformation of promising concepts into innovative treatments, thus accelerating the drug development process of diabetes.

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