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Streptozotocin-induced (STZ) Rat
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Streptozotocin-induced (STZ) Rat

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Cat. No.: DMM-001002

Status Age Sex
  • Live Mouse
  • Frozen Embryo
  • 4 weeks
  • 12 weeks
  • Customized Age
  • Male
  • Female
Product Overview
Model Description This knockout mutant of the Pdcd4 (programmed cell death 4) gene exhibits reduced cytokine secretion, lower susceptibility to LPS challenge and EAE, resistance to STZ- induced diabetes, and develops spontaneous lymphoma.
Strain Name B6.129S6-Pdcd4tm1Yhcn/J
Background Strain B6.129S6
SPF Yes
Genetic Modification Conventional knockout
Research Application Diabetes
Target Information
Target Name Pdcd4
Synonyms Programmed cell death 4
Gene ID 27250
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Ace Therapeutics has a team of experts in the field of endocrine and metabolic research, aiming to provide innovative preclinical contract research solutions to cope with diabetes and its complications. We provide customized solutions and technical support, enabling the transformation of promising concepts into innovative treatments, thus accelerating the drug development process of diabetes.

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  • 1-516-880-2558
  • 500-A Wheeler Rd, Hauppauge, NY 11788, USA
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