SIS3 HCl

SIS3 HCl

Cat. No.: DIA-0230248

Size: 50 mg Size: 500 mg Size: Customer Size
Product Information
CAS No. 521984-48-5
Formula C28H28ClN3O3
Molecular Weight 489.99
SMILES Cl.COC1=CC2=C(CN(CC2)C(=O)/C=C/C3=C([N](C)C4=NC=CC=C34)C5=CC=CC=C5)C=C1OC
Product Description SIS3, a novel specific inhibitor of Smad3, inhibits TGF-β and activin signaling by suppressing Smad3 phosphorylation without affecting the MAPK/p38, ERK, or PI3-kinase signaling pathways.
Format & Storage
Purity > 98%
Shipping Shipped on dry ice.
Storage Powder: -20 °C, 3 years; 4 °C, 2 years In solvent: -80 °C, 6 months; -20 °C, 1 month
Solubility Overview Soluble in DMSO
All of our services and products are intended for preclinical research use only and cannot be used to diagnose, treat or manage patients.
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Ace Therapeutics has a team of wellknown experts in the field of endocrine and metabolic research, aiming to provide innovative preclinical contract research solutions to cope with diabetes and its complications. We provide customized solutions and technical support, enabling the transformation of promising concepts into innovative treatments, thus accelerating the drug development process of diabetes.

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