Cat. No.: DAA-001231
| Product Information | |
|---|---|
| Product Name | Senescence β-Galactosidase Staining Kit |
| Description | The Senescence β-Galactosidase Staining Kit is designed to conveniently provide reagents needed to detect β-galactosidase activity at pH 6, a known characteristic of senescent cells. Papers have published using this kit in both cells and frozen tissue. The kit includes all reagents necessary for this assay. |
| Component | 10X Fixative Solution; 10X Staining Solution; 100X Solution A; 100X Solution B; X-Gal |
| Target Information | |
|---|---|
| Target Name | lacZ |
| UniProt No. | P00722 |
| Gene ID | 945006 |
| Target Description | Limited capacity to replicate is a defining characteristic of most normal cells and culminates in senescence, an arrested state in which the cell remains viable. Senescent cells are not stimulated to divide by serum or passage in culture, and senescence invokes a specific cell cycle profile that differs from most damage-induced arrest processes or contact inhibition. An enlarged cell size, expression of pH-dependent β-galactosidase activity, and an altered pattern of gene expression further characterize senescent cells. |
| Alternative Names | Lactase; β-gal |
| Shipping & Storage | |
|---|---|
| Sipping | Shipping on dry ice. |
| Storage | Store at -20°C. Please refer to protocols. |
