SB-203580

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Cat. No.: DIA-0230285

Size: 50 mg Size: 500 mg Size: Customer Size

Product Information
CAS No.	152121-47-6
Synonyms	RWJ 64809, PB 203580
Formula	C₂₁H₁₆FN₃OS
Molecular Weight	377.43
SMILES	C[S](=O)C1=CC=C(C=C1)C2=NC(=C([NH]2)C3=CC=NC=C3)C4=CC=C(F)C=C4
Product Description	SB203580 is a p38 MAPK inhibitor with IC50 of 0.3-0.5 μM in THP-1 cells, 10-fold less sensitive to SAPK3(106T) and SAPK4(106T) and blocks PKB phosphorylation with IC50 of 3-5 μM.

Format & Storage
Purity	> 99%
Shipping	Shipped on dry ice.
Storage	Powder: -20 °C, 3 years; 4 °C, 2 years In solvent: -80 °C, 6 months; -20 °C, 1 month
Solubility Overview	Soluble in DMSO

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